Now showing items 1-5 of 5
Liver response to low-hexachlorobenzene exposure in protein- or energy-restricted rats
(Food and Chemical Toxicology, 1991-12-01) [Artigo]
The individual effects of protein deficiency and energy restriction on liver response to low-hexachlorobenzene (HCB) exposure were investigated in adult male Wistar rats. In rats fed either the low-protein or control diet, ...
Dose-response of diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] in the urothelial mucosa of Wistar rats
(Toxicology, 2013-08-20) [Artigo]
Diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] is a herbicide that induced urothelial tumors in the urinary bladder of Wistar rats fed 2500. ppm during a long-term study. The currently suggested non-genotoxic mode of ...
Chromosomal imbalances in successive moments of human bladder urothelial carcinoma
(Urologic Oncology: Seminars and Original Investigations, 2013-08-01) [Artigo]
Objective: To understand developmental characteristics of urinary bladder carcinomas (UBC) by evaluating genomic alterations and p53 protein expression in primary tumors, their recurrences, and in the morphologically normal ...
Brazilian experience with the medium-term multi-organ bioassay: Scientific and regulatory developments
(Asian Pacific Journal of Cancer Prevention, 2010-08-25) [Trabalho apresentado em evento]
In 1996 the Brazilian Institute for the Environment (IBAMA) officially adopted a variation of the multiorgan initiation-promotion DMBDD bioassay as a valid source of evidence of the carcinogenic potential of pesticides. ...
Macrophage activity and histopathology of the lymphohematopoietic organs in male Wistar rats orally exposed to single or mixed pesticides
(Journal of Environmental Science and Health - Part B: Pesticides, Food Contaminants, and Agricultural Wastes, 2013-07-01) [Artigo]
The noxious effects of low or effective dose exposure to single or mixed pesticides on macrophage activity and the lymphohematopoietic organs were investigated. Male Wistar rats were orally exposed to dichlorvos, dicofol, ...