Now showing items 1-6 of 6
Antimicrobial endodontic compounds do not modulate alkylation-induced genotoxicity and oxidative stress in vitro
(Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, 2006-08-01) [Artigo]
Objective: To investigate if formocresol, paramonochlorophenol, or calcium hydroxide modulate the genotoxic effects induced by the oxidatively damaging agent hydrogen peroxide (H 2O 2) or the alkylating agent methyl ...
DNA damage in multiple organs after exposure to chlorhexidine in Wistar rats
(International Journal of Hygiene and Environmental Health, 2007-03-01) [Artigo]
Since chlorhexidine is effective against microorganisms, it is widely recommended in dentistry. However, studies have provided evidence that chlorhexidine is toxic for a variety of cell types. In order to identify potential ...
Lack of genotoxicity of formocresol, paramonochlorophenol, and calcium hydroxide on mammalian cells by comet assay
(Journal of Endodontics, 2004-08-01) [Artigo]
Formocresol, paramonochlorophenol, and calcium hydroxide are widely used in dentistry because of their antibacterial activities in root canal disinfection. However, the results of genotoxicity studies using these materials ...
Study of DNA damage induced by dental bleaching agents in vitro
(Brazilian Oral Research, 2006-06-01) [Artigo]
Dental bleaching is a simple and conservative procedure for aesthetic restoration of vital and non-vital discolored teeth. Nevertheless, a number of studies have demonstrated the risk of tissue damage from the contact of ...
Fluoride does not induce DNA breakage in Chinese hamster ovary cells in vitro.
(Pesquisa Odontológica Brasileira = Brazilian Oral Research, 2004-07-01) [Artigo]
Fluoride has been widely used in dentistry because it is a specific and effective caries prophylactic agent. However, excess fluoride may represent a hazard to human health, especially by causing injury to genetic material. ...
Lack of DNA damage induced by fluoride on mouse lymphoma and human fibroblast cells by single cell gel (comet) assay
(Brazilian Dental Journal, 2006-12-01) [Artigo]
Fluoride has widely been used in Dentistry because it is a specific and effective caries prophylactic agent. However, excess fluoride may represent a hazard to human health, especially by causing injury on genetic apparatus. ...