Now showing items 1-6 of 6
Analysis of DNA damage induced by aflatoxin B1 in Dunkin-Hartley guinea pigs
(Mycopathologia, 2007-05-01) [Artigo]
Aflatoxin B1 (AFB1) is among the most potent naturally occurring carcinogens and classified as a group I carcinogen. Since the ingestion of aflatoxin-contaminated food is associated with several liver diseases, the aim of ...
DNA damage and nitric oxide synthesis in experimentally infected Balb/c mice with Trypanosoma cruzi
(Experimental Parasitology, 2007-07-01) [Artigo]
This study aimed to evaluate whether experimental Chagas disease in acute phase under benznidazole therapy can cause DNA damage in peripheral blood, liver, heart, and spleen cells or induce nitric oxide synthesis in spleen ...
DNA repair gene polymorphism is associated with the genetic basis of atherosclerotic coronary artery disease
(Cardiovascular Pathology, 2011-01-01) [Artigo]
Background: Atherosclerotic coronary artery disease (CAD) is a multifactorial process that appears to be caused by the interaction of environmental risk factors with multiple predisposing genes. It is nowadays accepted ...
Study on the mutagenicity and antimutagenicity of a natural food colour (annatto) in mouse bone marrow cells
(Food and Chemical Toxicology, 2003-02-01) [Artigo]
Most manufactured foods contain chemicals added as a deliberate part of the manufacturing process. The aims of the present study were to evaluate the mutagenicity and antimutagenicity of annatto, a natural pigment extracted ...
Genotoxicity in primary human peripheral lymphocytes after exposure to regular and white mineral trioxide aggregate
(Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, 2006-11-01) [Artigo]
Objective: Taking into consideration that DNA damage plays an important role in carcinogenesis, the purpose of this study was to evaluate whether regular and white mineral trioxide aggregate (MTA) are able to induce genetic ...
Influence of endogenous and synthetic female sex hormones on human blood cells in vitro studied with comet assay
(Toxicology in Vitro, 2007-08-01) [Artigo]
The comet assay has been conducted with numerous cell lines to assess in vitro genotoxicity. In order to use the comet assay as part of an in vitro test for evaluating genotoxicity, however, there are cell-specific factors ...