Now showing items 11-20 of 56
DNA damage and nitric oxide synthesis in experimentally infected Balb/c mice with Trypanosoma cruzi
(Experimental Parasitology, 2007-07-01) [Artigo]
This study aimed to evaluate whether experimental Chagas disease in acute phase under benznidazole therapy can cause DNA damage in peripheral blood, liver, heart, and spleen cells or induce nitric oxide synthesis in spleen ...
Diuron lacks promoting potential in a rat liver bioassay
(Toxicologic Pathology, 2007-01-01) [Artigo]
The promoting activity of the herbicide Diuron was evaluated in a medium-term rat liver carcinogenesis bioassay that uses as endpoint immunohistochemically identified glutathione S-transferase positive (GST-P+) foci. Male ...
MS222 does not induce primary DNA damage in fish
(Aquaculture International, 2007-04-01) [Artigo]
The genotoxicity of the anaesthetic MS222 (tricaine) was analysed in fish under both in vivo and in vitro conditions. Based on results of the single cell gel/Comet assay, MS222 had no direct genotoxic effect on the ...
Human bcl-2 expression, cleaved caspase-3, and KSHV LANA-1 in Kaposi sarcoma lesions
(American Journal of Clinical Pathology, 2007-11-01) [Artigo]
We aimed to evaluate the frequency of Kaposi sarcoma (KS)-associated herpesvirus (KSHV) infection in KS lesions in patients from Brazil. In addition, expression of human bcl-2, cleaved caspase-3, and KSHV latency-associated ...
A problotic strain of enterecoccus faecium CRL183 reduces DMH-induced large intestinal tumors in male Wistar rats
(Ejc Supplements, 2007-09-01) [Resumo]
Morphometric study of placental villi and vessels in women with mild hyperglycemia or gestational or overt diabetes
(Diabetes Research and Clinical Practice, 2007-10-01) [Artigo]
In this study, morphometric measures of placental terminal villi and villous vessels were compared in overt, as well as gestational diabetes mellitus, and mild hyperglycemia diagnosed by oral 100 g glucose tolerance test ...
Tomato-oleoresin supplement prevents doxorubicin-induced cardiac myocyte oxidative DNA damage in rats
(Mutation Research: Genetic Toxicology and Environmental Mutagenesis, 2007-07-10) [Artigo]
Doxorubicin (DOX) is an efficient chemotherapeutic agent used against several types of tumors; however, its use is limited due to severe cardiotoxicity. Since it is accepted that reactive oxygen species are involved in ...
Occurrence of coagulase-positive Staphylococcus in various food products commercialized in Botucatu, SP, Brazil and detection of toxins from food and isolated strains
(Food Control, 2007-06-01) [Artigo]
The aim of this work was to assess the microbiological quality of commercialized desserts, sandwiches and finger food in Botucatu, SP, for human consumption. A total of 172 food samples were analyzed for fecal coliforms ...
Paracoccidioidomycosis: No genetic damage in human peripheral blood cells of patients assessed by single-cell gel (comet) assay
(Revista da Sociedade Brasileira de Medicina Tropical, 2007-07-01) [Artigo]
Paracoccidioidomycosis is a systemic fungal infection caused by Paracoccidioides brasiliensis. As infectious diseases can cause DNA damage, the authors aimed at analyzing DNA breakage in peripheral blood cells of patients ...
Differential response related to genotoxicity between eggplant (Solanum melanogena) skin aqueous extract and its main purified anthocyanin (delphinidin) in vivo
(Food and Chemical Toxicology, 2007-05-01) [Artigo]
Anthocyanins are the largest group of water-soluble pigments in the plant kingdom. A number of studies have demonstrated that anthocyanins present antioxidant capacity and show inhibitory effects on the growth of some ...