Now showing items 41-50 of 192
Does the tumour microenvironment alter tumorigenesis and clinical response in transmissible venereal tumour in dogs?
(Veterinary and Comparative Oncology, 2018-09-01) [Artigo]
The canine transmissible venereal tumour (CTVT) is a transmissible cancer that is spread naturally between dogs, with the ability to develop and evade the immune system, despite strict immune surveillance of the host. ...
The prostate response to prolactin modulation in adult castrated rats subjected to testosterone replacement
(Journal of Molecular Histology, 2017-12-01) [Artigo]
Despite the androgenic dependence, other hormones, growth factors, and cytokines are necessary to support prostatic growth and maintain the glandular structure; among them, prolactin is a non-steroidal hormone secreted ...
Protein Carbonylation Is Related to Liver Damage in an Experimental Model of Obesity
(Faseb Journal, 2017-04-01) [Resumo]
Fibrosis-associated hepatocarcinogenesis revisited: Establishing standard medium-term chemically-induced male and female models
(PLoS ONE, 2018-09-01) [Artigo]
Hepatocellular carcinoma causes ~10% of all cancer-related deaths worldwide, usually emerging in a background of liver fibrosis/cirrhosis (70%-90% of cases). Chemically-induced mouse models for fibrosis-associated ...
Cell block sensitivity for immunohistochemical detection of cytokeratin 5, oestrogen and progesterone receptors in canine primary mammary carcinoma
(Austral Journal Of Veterinary Sciences, 2017-01-01) [Artigo]
Mammary carcinomas are relatively common ailments among female canines aged around 10 years old, presenting an important morbidity with an average survival of five years. The cytoinclusion technique is frequently employed ...
Expression patterns of CD56+and CD16+cells in renal transplant biopsies with acute rejection: Associations with microcirculation injuries and graft survival
(Nephrology, 2017-12-01) [Artigo]
BackgroundThe study investigated whether immunohistochemical features of interstitial and glomerular CD56 and CD16 infiltrates - NK cells markers - could be associated with microcirculation injury scores - peritubular ...
Cytotoxic and toxicogenomic effects of silibinin in bladder cancer cells with different TP53 status
(Journal Of Biosciences, 2017-03-01) [Artigo]
Silibinin is a natural phenol found in the seeds of the milk thistle plant. Recent data have shown its effectiveness for preventing/treating bladder tumours. Therefore, in this study we investigated the cytotoxic and ...
Exploring pathways for sustained melanogenesis in facial melasma: an immunofluorescence study
(International Journal of Cosmetic Science, 2018-08-01) [Artigo]
Background: The physiopathology of epidermal hypermelanization in melasma is not completely understood. Several cytokines and growth factors are increased in skin with melasma, nevertheless, nor the pathways involved in ...
Strength training prior to muscle injury potentiates low-level laser therapy (LLLT)-induced muscle regeneration
(Lasers in Medical Science, 2017-02-01) [Artigo]
We evaluated whether strength training (ST) performed prior to skeletal muscle cryolesion would act as a preconditioning, improving skeletal muscle regeneration and responsiveness to low-level laser therapy (LLLT). Wistar ...
Common chromosomal imbalances and stemness-related protein expression markers in endometriotic lesions from different anatomical sites: the potential role of stem cells
(Human Reproduction, 2012-11-01) [Artigo]
Endometriosis is a multifactorial gynecological disease characterized by the presence of functional endometrium-like tissue in ectopic sites. Several studies have focused on elucidating the immunological, endocrine, ...