Now showing items 1-10 of 20
Absence of DNA damage in multiple organs after oral exposure to fluoride in Wistar rats
(Bulletin of Environmental Contamination and Toxicology, 2006-11-01) [Artigo]
Antimicrobial endodontic compounds do not modulate alkylation-induced genotoxicity and oxidative stress in vitro
(Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, 2006-08-01) [Artigo]
Objective: To investigate if formocresol, paramonochlorophenol, or calcium hydroxide modulate the genotoxic effects induced by the oxidatively damaging agent hydrogen peroxide (H 2O 2) or the alkylating agent methyl ...
Biocompatibility of glass-ionomer cements using mouse lymphoma cells in vitro
(Journal of Oral Rehabilitation, 2006-12-01) [Artigo]
Glass-ionomer cements are widely used in dentistry as restorative materials and adhesives for composite restorations. A number of genotoxicity studies have been conducted using these materials with results conflicting so ...
Biocompatibility of gutta-percha solvents using in vitro mammalian test-system
(Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, 2007-05-01) [Artigo]
Objectives. Taking into consideration that DNA damage and cellular death play important roles during carcinogenesis, the purpose of the present study was to evaluate in vitro genotoxic or cytotoxic effects of chloroform ...
Cigarette smoke affects apoptosis in rat tongue mucosa: Role of bcl-2 gene family
(Journal of Molecular Histology, 2005-10-01) [Artigo]
While it has been clearly demonstrated that smoking is the most significant exogenous factor involved in oral carcinogenesis, little is known about the global molecular and cellular changes that occur prior to the appearance ...
DNA damage in multiple organs after exposure to chlorhexidine in Wistar rats
(International Journal of Hygiene and Environmental Health, 2007-03-01) [Artigo]
Since chlorhexidine is effective against microorganisms, it is widely recommended in dentistry. However, studies have provided evidence that chlorhexidine is toxic for a variety of cell types. In order to identify potential ...
Ex vivo biocompatibility tests of regular and white forms of mineral trioxide aggregate
(International Endodontic Journal, 2006-01-01) [Artigo]
Aim: To examine the genotoxicity and cytotoxicity of regular and white mineral trioxide aggregate (MTA) ex vivo by the single-cell gel (comet) assay and trypan blue exclusion test, respectively. Methodology: Aliquots of 1 ...
Expression of cell cycle regulatory proteins in epithelial components of dental follicles
(Journal of Molecular Histology, 2006-05-01) [Artigo]
Dental follicle is a component of tooth germs, which remain adjacent to the crown of unerupted or impacted teeth. Under the influence of pathologic changes, however, dental follicles that possess reduced epithelium can ...
Lack of genotoxicity of formocresol, paramonochlorophenol, and calcium hydroxide on mammalian cells by comet assay
(Journal of Endodontics, 2004-08-01) [Artigo]
Formocresol, paramonochlorophenol, and calcium hydroxide are widely used in dentistry because of their antibacterial activities in root canal disinfection. However, the results of genotoxicity studies using these materials ...
Lack of effect of prior treatment with fluoride on genotoxicity of two chemical agents in vitro
(Caries Research, 2007-01-01) [Artigo]
The goal of this study was to investigate the ability of fluoride to modulate the genotoxic effects induced by the oxidative agent hydrogen peroxide (H2O2) and the alkylating agent methyl methanesulfonate (MMS) in vitro ...