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dc.contributor.authorEstevão, Lígia Reis Moura
dc.contributor.authorMedeiros, Juliana Pinto De
dc.contributor.authorSimões, Ricardo Santos
dc.contributor.authorArantes, Rosa Maria Esteves
dc.contributor.authorRachid, Milene Alvarenga
dc.contributor.authorSilva, Regildo Márcio Gonçalves Da
dc.contributor.authorMendonça, Fábio De Souza
dc.contributor.authorEvêncio-neto, Joaquim
dc.date.accessioned2015-08-21T17:54:44Z
dc.date.available2015-08-21T17:54:44Z
dc.date.issued2015-04-01
dc.identifierhttp://dx.doi.org/10.1590/S0102-865020150040000008
dc.identifier.citationActa Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 30, n. 4, p. 289-295, 2015.
dc.identifier.issn0102-8650
dc.identifier.urihttp://hdl.handle.net/11449/127258
dc.description.abstractPURPOSE: To evaluate wound contraction and the concentration of mast cells in skin wounds treated with 5% BPT essential oil-based ointment in rats. METHODS: Twenty rats, male, of adult age, were submitted to skin surgery on the right (RA) and left antimeres (LA) of the thoracic region. They were divided into two groups: control (RA - wounds receiving daily topical application of vaseline and lanolin) and treated (LA - wounds treated daily with the topical ointment). The skin region with wounds were collected at days 4, 7, 14 and 21 after surgery. Those were fixed in 10% formaldehyde and later processed for paraffin embedding. Sections were obtained and stained by H.E for histopathology analysis. The degree of epithelial contraction was measured and mast cell concentration were also evaluated. RESULTS: The treated group showed higher mast cell concentrations (p<0.05) associated with increased contraction at day 7 and 14 respectively. CONCLUSION: Ointment containing 5% Brazilian pepper tree oil increases mast cell concentration and promotes skin wound contraction in rats.en
dc.format.extent289-295
dc.language.isoeng
dc.publisherSociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.relation.ispartofActa Cirurgica Brasileira
dc.sourceSciELO
dc.subjectWound Healingen
dc.subjectPhytotherapyen
dc.subjectMast Cellsen
dc.subjectSkinen
dc.subjectRatsen
dc.titleMast cell concentration and skin wound contraction in rats treated with Brazilian pepper essential oil (Schinus terebinthifolius Raddi)en
dc.typeArtigo
dc.contributor.institutionUFRPE
dc.contributor.institutionUNIFESP
dc.contributor.institutionUFMG
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.description.affiliationUFRPE
dc.description.affiliationUNIFESP
dc.description.affiliationUFMG
dc.description.affiliationUNESP
dc.description.affiliationUnespUNESP
dc.identifier.doi10.1590/S0102-865020150040000008
dc.identifier.scieloS0102-86502015000400289
dc.rights.accessRightsAcesso aberto
dc.identifier.fileS0102-86502015000400289.pdf
dc.identifier.lattes5285324361162578
dc.identifier.orcid0000-0002-0300-0247
unesp.author.lattes5285324361162578[6]
unesp.author.orcid0000-0002-0300-0247[6]
dc.relation.ispartofjcr0.933
dc.relation.ispartofsjr0,395
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