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dc.contributor.advisorQueiroz, Luzia Helena [UNESP]
dc.contributor.authorCasagrande, Daiene Karina Azevedo [UNESP]
dc.date.accessioned2015-10-06T13:02:53Z
dc.date.available2015-10-06T13:02:53Z
dc.date.issued2014-07-27
dc.identifier.citationCASAGRANDE, Daiene Karina Azevedo. Ocorrência da raiva e de anticorpos antirrábicos em morcegos do noroeste de São Paulo. 2014. 58 f. , 2014.
dc.identifier.urihttp://hdl.handle.net/11449/128018
dc.description.abstractRabies is a major zoonosis which affects mammals from all over the world and has bats as reservoirs of, both urban and rural areas. Since 1998 cases of rabies in bats have been recorded in the northwest region of São Paulo State, predominantly in urban areas. The objective of this study was to investigate the circulation of rabies in bats in the northwestern region of São Paulo by searching of the virus in different species and the presence of rabies neutralizing antibodies in vampire bats. A total of 1,490 brain samples from bats were sent to the Laboratory of Rabies and 125 serum samples of vampire bats from four shelters in the region were examined from 2008 to 2012. The virus presence was determined by fluorescent antibodies test (FAT) and mouse inoculation test (MIT) while neutralizing antibodies were determined by the simplified microneutralization (SFIMT) in BHK21 cells. Rabies virus was detected in 26 (1.97%) out of 1,314 non-hematophagous bats and in none of the 176 vampire bats examined. Only 7% (9/125) of vampire bats had antibody titers above 0.5UI/ml, 65% (81/125) had low titers (0.10 to 0.5UI/ml) and 28% (35/125) were negative. The positivity rate observed was 1.74% which is above the average rate of 1.3% recorded previously in this region. The high percentage of vampire bats with neutralizing antibodies to rabies virus indicates a recent exposure to the virus which confirms that surveillance measures must be in place to avoid an increase in disease occurrenceen
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent58 f.
dc.language.isopor
dc.publisherUniversidade Estadual Paulista (UNESP)
dc.sourceAleph
dc.subjectMorcegopt
dc.subjectVírus da hidrofobiapt
dc.subjectImunoglobulinaspt
dc.subjectSorologia veterinariapt
dc.subjectPesquisa experimentalpt
dc.subjectAntibodiespt
dc.titleOcorrência da raiva e de anticorpos antirrábicos em morcegos do noroeste de São Paulopt
dc.typeDissertação de mestrado
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.rights.accessRightsAcesso aberto
unesp.graduateProgramCiência Animal - FMVApt
unesp.knowledgeAreaMedicina Veterinária Preventiva e produção animalpt
unesp.researchAreaEpidemiologia, etiopatogenia, diagnóstico e controle das enfermidades animaispt
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina Veterinária, Araçatubapt
dc.identifier.aleph000849248
dc.identifier.filehttp://www.athena.biblioteca.unesp.br/exlibris/bd/cathedra/16-09-2015/000849248.pdf
dc.identifier.capes33004021075P8
dc.identifier.lattes0299583248667294
unesp.author.lattes0299583248667294
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