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dc.contributor.authorZieri, Rodrigo [UNESP]
dc.contributor.authorFranco-Belussi, Lilian [UNESP]
dc.contributor.authorSantos, Lia Raquel de Souza
dc.contributor.authorTaboga, Sebastião Roberto [UNESP]
dc.contributor.authorOliveira, Classius de [UNESP]
dc.date.accessioned2015-10-21T13:13:41Z
dc.date.available2015-10-21T13:13:41Z
dc.date.issued2015-01-01
dc.identifierhttp://booksandjournals.brillonline.com/content/journals/10.1163/15707563-00002457
dc.identifier.citationAnimal Biology. Leiden: Brill Academic Publishers, v. 65, n. 1, p. 21-32, 2015.
dc.identifier.issn1570-7555
dc.identifier.urihttp://hdl.handle.net/11449/128796
dc.description.abstractMelanomacrophages and melanocytes are able to modify pigment intensity on the body surface as a response to temperature change, hibernation, hypoxia, infection, oxidative stress and exogenous use of hormones. This study evaluated the effect of the sex hormones 17 beta-estradiol and testosterone cypionate on the hepatic melanomacrophages and testicular melanocytes of Eupemphix nattereri under hyperestrogenic and hyperandrogenic conditions, eight days after daily hormonal administration as well as after a 15-day recovery period. Animals were injected subcutaneously with 17 beta-estradiol, testosterone cypionate or the carrier medium (as control). Histological analysis was used to examine the effect of the treatments. The results show that sex hormones altered the pigmentation of hepatic melanomacrophages and testicular melanocytes. Both liver melanomacrophages and testicular melanocytes in E. nattereri males displayed increased pigmentation after testosterone treatment, while estradiol decreased liver pigmentation only. This study describes, for the first time, the effects of sex hormones on visceral pigmentation of anura, showing the responsiveness of melanocytes and melanomacrophages to sex hormones.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent21-32
dc.language.isoeng
dc.publisherBrill Academic Publishers
dc.relation.ispartofAnimal Biology
dc.sourceWeb of Science
dc.subjectEstradiolen
dc.subjectEupemphix nattererien
dc.subjectMelaninen
dc.subjectMelanocytesen
dc.subjectMelanomacrophagesen
dc.subjectTestosteroneen
dc.titleSex hormones change visceral pigmentation in Eupemphix nattereri (Anura): effects in testicular melanocytes and hepatic melanomacrophagesen
dc.typeArtigo
dcterms.rightsHolderBrill Academic Publishers
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionInstituto Federal Goiano (IFGoiano)
dc.description.affiliationUnespUniversidade Estadual Paulista, Departamento de Biologia, Instituto de Biociências, Letras e Ciências Exatas de São José do Rio Preto
dc.identifier.doihttp://dx.doi.org/10.1163/15707563-00002457
dc.identifier.wosWOS:000350996600003
dc.rights.accessRightsAcesso restrito
dc.description.sponsorshipIdFAPESP: 2009/13925-7
dc.description.sponsorshipIdFAPESP: 2005/02919-5
dc.description.sponsorshipIdCNPq: 475248/2007-4
dc.description.sponsorshipIdCNPq: 306123/2012-6
dc.description.sponsorshipIdFAPESP: 2014/00946-4
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências Letras e Ciências Exatas, São José do Rio Pretopt
dc.identifier.lattes1445259468526188
dc.identifier.lattes5731856650217859
dc.identifier.orcid0000-0002-0970-4288
unesp.author.lattes1445259468526188
unesp.author.lattes5731856650217859
unesp.author.orcid0000-0002-2029-7900[5]
unesp.author.orcid0000-0002-0970-4288[4]
dc.relation.ispartofjcr1.069
dc.relation.ispartofsjr0,294
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