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dc.contributor.authorBadial, Peres Ramos [UNESP]
dc.contributor.authorCisneros-Àlvarez, Luis Emiliano [UNESP]
dc.contributor.authorBrandão, Cláudia Valéria Seullner [UNESP]
dc.contributor.authorRanzani, José Joaquim Titton [UNESP]
dc.contributor.authorTomaz, Mayana A. R. V. [UNESP]
dc.contributor.authorMachado, Vania Maria [UNESP]
dc.contributor.authorBorges, Alexandre Secorun [UNESP]
dc.date.accessioned2015-12-07T15:31:58Z
dc.date.available2015-12-07T15:31:58Z
dc.date.issued2015
dc.identifierhttp://dx.doi.org/10.1111/vop.12222
dc.identifier.citationVeterinary Ophthalmology, v. 18, n. 5, p. 385-392, 2015.
dc.identifier.issn1463-5224
dc.identifier.urihttp://hdl.handle.net/11449/131141
dc.description.abstractThe aim of this study was to compare ocular dimensions, corneal curvature, and corneal thickness between horses affected with hereditary equine regional dermal asthenia (HERDA) and unaffected horses. Five HERDA-affected quarter horses and five healthy control quarter horses were used. Schirmer's tear test, tonometry, and corneal diameter measurements were performed in both eyes of all horses prior to ophthalmologic examinations. Ultrasonic pachymetry was performed to measure the central, temporal, nasal, dorsal, and ventral corneal thicknesses in all horses. B-mode ultrasound scanning was performed on both eyes of each horse to determine the dimensions of the ocular structures and to calculate the corneal curvature. Each corneal region examined in this study was thinner in the affected group compared with the healthy control group. However, significant differences in corneal thickness were only observed for the central and dorsal regions. HERDA-affected horses exhibited significant increases in corneal curvature and corneal diameter compared with unaffected animals. The ophthalmologic examinations revealed mild corneal opacity in one eye of one affected horse and in both eyes of three affected horses. No significant between-group differences were observed for Schirmer's tear test, intraocular pressure, or ocular dimensions. Hereditary equine regional dermal asthenia-affected horses exhibit decreased corneal thickness in several regions of the cornea, increased corneal curvature, increased corneal diameter, and mild corneal opacity. Additional research is required to determine whether the increased corneal curvature significantly impacts the visual accuracy of horses with HERDA.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent385-392
dc.language.isoeng
dc.publisherAmerican College Of Veterinary Ophthalmologists.
dc.relation.ispartofVeterinary Ophthalmology
dc.sourcePubMed
dc.subjectBiometryen
dc.subjectCorneal pachymetryen
dc.subjectCyclophilin ben
dc.subjectHereditary equine regional dermal astheniaen
dc.subjectHorsesen
dc.subjectKeratometryen
dc.titleOcular dimensions, corneal thickness, and corneal curvature in quarter horses with hereditary equine regional dermal astheniaen
dc.typeArtigo
dcterms.rightsHolderAmerican College Of Veterinary Ophthalmologists.
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationDepartment of Veterinary Clinical Science, UNESP - Univ Estadual Paulista, Distrito de Rubião Júnior, Botucatu, São Paulo, Brazil.
dc.description.affiliationDepartment of Animal Reproduction and Veterinary Radiology, UNESP - Univ Estadual Paulista, Distrito de Rubião Júnior, Botucatu, São Paulo, Brazil.
dc.description.affiliationDepartment of Veterinary Surgery and Anesthesiology, UNESP - Univ Estadual Paulista, Distrito de Rubião Júnior, Botucatu, São Paulo, Brazil.
dc.description.affiliationUnespDepartment of Veterinary Clinical Science, UNESP - Univ Estadual Paulista, Distrito de Rubião Júnior, Botucatu, São Paulo, Brazil.
dc.description.affiliationUnespDepartment of Animal Reproduction and Veterinary Radiology, UNESP - Univ Estadual Paulista, Distrito de Rubião Júnior, Botucatu, São Paulo, Brazil.
dc.description.affiliationUnespDepartment of Veterinary Surgery and Anesthesiology, UNESP - Univ Estadual Paulista, Distrito de Rubião Júnior, Botucatu, São Paulo, Brazil.
dc.identifier.doi10.1111/vop.12222
dc.rights.accessRightsAcesso restrito
dc.description.sponsorshipIdFAPESP: 2009/17764-8
dc.description.sponsorshipIdFAPESP: 2010/08774-7
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina Veterinária e Zootecnia, Botucatupt
dc.identifier.lattes6814417676840286
dc.identifier.lattes9643433706163946
dc.identifier.pubmed25338739
unesp.author.lattes6814417676840286
unesp.author.lattes9643433706163946[7]
unesp.author.orcid0000-0001-6256-8089[7]
dc.relation.ispartofsjr0,692
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