Alcohol levels in cerebrospinal fluid and blood samples from patients under pathological conditions
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Data
1992-01-01
Autores
Agapejev, S. [UNESP]
Vassilieff, I. [UNESP]
Curi, P. R. [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Munksgaard Int Publ Ltd
Resumo
We measured alcohol levels by the Cordebard method in 148 CSF samples from individuals who had abstained from alcohol for at least 7 days prior to the beginning of the study. Each blood sample was accompanied by a CSF sample from the same patient. CSF samples found to be normal after analysis were used as controls. Mean alcohol concentration in blood did not differ significantly between the control group and the groups with altered CSF. The group with altered CSF had statistically higher alcohol levels in CSF than in blood. CSF lactate, glucose and protein levels were not correlated with alcohol level. The results suggest the presence of endogenous alcohol in the CSF, with levels increasing in the presence of pathological processes involving the nervous system.
Descrição
Palavras-chave
Alcohol, Blood, Cerebrospinal fluid, Cordebard method, Adolescent, Adult, Aged, Controlled study, Female, Human, Major clinical study, Male, Metabolism, Neurologic disease, Priority journal, School child, Adolescent, Adult, Aged, Blood Glucose, Blood-Brain Barrier, Central Nervous System Diseases, Child, Ethanol, Female, Human, Lactates, Lactic Acid, Male, Middle Age, Reference Values
Como citar
Acta Neurologica Scandinavica, v. 86, n. 5, p. 496-500, 1992.