Now showing items 1-2 of 2
Caracterização físico-química de complexo de inclusão entre hidroximetilnitrofurazona e hidroxipropil-beta-ciclodextrina
(Química Nova, 2008-01-01) [Artigo]
Hydroxymethylnitrofurazone (NFOH) is a prodrug that is active against Trypanosoma cruzi. It however presents low solubility and high toxicity. Hydroxypropyl-beta-cyclodextrin (HP-beta-CD) can be used as a drug-delivery ...
Improvement of the oral praziquantel anthelmintic effect by cyclodextrin complexation
(Journal of Drug Targeting, 2010-01-01) [Artigo]
Schistosomiasis is a parasitic disease which kills a half million people per year, a I I over the world. Praziquantel (PZQ) is the drug-of-choice for schistosomiasis because of its effectiveness, ease of administration, ...