Now showing items 1-4 of 4
Bupivacaine in alginate and chitosan nanoparticles: An in vivo evaluation of efficacy, pharmacokinetics, and local toxicity
(Journal of Pain Research, 2018-04-06) [Artigo]
Objective: This study reports a preclinical evaluation of an alginate/chitosan nanoparticle formulation containing NovaBupi®, a racemic bupivacaine (BVC) containing 25% dextrobupivacaine and 75% levobupivacaine. Methods: ...
Layer-by-layer films containing emodin or emodin encapsulated in liposomes for transdermal applications
(Colloids and Surfaces B: Biointerfaces, 2018-02-01) [Artigo]
Dermal drug release systems are an important area of research because they can be applied to the skin in a non-invasive procedure using a lower concentration of drugs. In this study, we have developed two types of ...
Development of egg PC/cholesterol/alpha-tocopherol liposomes with ionic gradients to deliver ropivacaine
(Journal Of Liposome Research, 2016-01-02) [Artigo]
Context: Ropivacaine (RVC) is an aminoamide local anesthetic widely used in surgical procedures. Studies with RVC encapsulated in liposomes and complexed in cyclodextrins have shown good results, but in order to use RVC ...
Initial Development and Characterization of PLGA Nanospheres Containing Ropivacaine
(Journal of Biological Physics, 2007-12-01) [Artigo]
Local anesthetics are able to induce pain relief by binding to the sodium channels of excitable membranes, blocking the influx of sodium ions and the propagation of the nervous impulse. Ropivacaine (RVC) is an amino amide, ...