Now showing items 1-3 of 3
Anestésicos locais: interação com membranas biológicas e com o canal de sódio voltagem-dependente
(Química Nova, 2008-01-01) [Artigo]
Many theories about the mechanism of action of local anesthetics (LA) are described in the literature. Two types of theories can be distinguished: those that focus on the direct effects of LA on their target protein in the ...
Benzocaine-loaded polymeric nanocapsules: Study of the anesthetic activities
(Journal of Pharmaceutical Sciences, 2012-03-01) [Artigo]
This paper describes a comparison of different polymeric nanocapsules (NCs) prepared with the polymers poly(d,l-lactide-co-glycolide), poly(l-lactide) (PLA), and poly(e-caprolactone) and used as carrier systems for the ...
Poly(Lactide-co-Glycolide) Nanocapsules Containing Benzocaine: Influence of the Composition of the Oily Nucleus on Physico-Chemical Properties and Anesthetic Activity
(Pharmaceutical Research, 2011-08-01) [Artigo]
The aim of this work was to investigate the influence of the oily nucleus composition on physico-chemical properties and anesthetic activity of poly (lactide-co-glycolide) nanocapsules with benzocaine.Nanocapsules containing ...