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Ki-67 labeling in canine perianal glands neoplasms: A novel approach for immunohistological diagnostic and prognostic
(BMC Veterinary Research, 2013-04-20) [Artigo]
Background: The antibody Ki-67 is a reliable and easy tool to accurately assess the growth fraction of neoplasms in humans and animals, and it has been used to predict the clinical outcome. Therefore, the aim of the present ...
Zymographic patterns of MMP-2 and MMP-9 in the CSF and cerebellum of dogs with subacute distemper leukoencephalitis
(Veterinary Immunology and Immunopathology, 2013-07-15) [Artigo]
Distemper leukoencephalitis is a disease caused by the canine distemper virus (CDV) infection. It is a demyelinating disease affecting mainly the white matter of the cerebellum and areas adjacent to the fourth ventricle; ...
Asymptomatic dogs are highly competent to transmit Leishmania (Leishmania) infantum chagasi to the natural vector
(Veterinary Parasitology, 2013-09-23) [Artigo]
We evaluated the ability of dogs naturally infected with Leishmania (Leishmania) infantum chagasi to transfer the parasite to the vector and the factors associated with transmission. Thirty-eight infected dogs were confirmed ...
Pro-inflammatory cytokines predominate in the brains of dogs with visceral leishmaniasis: A natural model of neuroinflammation during systemic parasitic infection
(Veterinary Parasitology, 2013-02-18) [Artigo]
Visceral leishmaniasis is a multisystemic zoonotic disease that can manifest with several symptoms, including neurological disorders. To investigate the pathogenesis of brain alterations occurring during visceral leishmaniasis ...
Influence of apoptosis on the cutaneous and peripheral lymph node inflammatory response in dogs with visceral leishmaniasis
(Veterinary Parasitology, 2013-02-18) [Artigo]
In canine visceral leishmaniasis (CVL), the abnormalities most commonly observed in clinical examination on the animals are lymphadenomegaly and skin lesions. Dogs are the main domestic reservoir for the protozoon Leishmania ...
High concentrations of glucose reduce the oxidative metabolism of dog neutrophils in vitro
(BMC Veterinary Research, 2013-02-06) [Artigo]
Background: Dogs are commonly affected by hyperglycemic conditions. Hyperglycemia compromises the immune response and favors bacterial infections; however, reports on the effects of glucose on neutrophil oxidative metabolism ...
Neutrophil dysfunction varies with the stage of canine visceral leishmaniosis
(Veterinary Parasitology, 2013-09-01) [Artigo]
Canine visceral leishmaniosis (CVL) causes a dependent-stage alteration in neutrophil oxidative metabolism. When production of reactive oxygen species (ROS) exceeds the antioxidant capacity of neutrophils, apoptosis is ...
Improvement in clinical signs and cellular immunity of dogs with visceral leishmaniasis using the immunomodulator P-MAPA
(Acta Tropica, 2013-09-01) [Artigo]
This study investigated the immunotherapeutic potential of the protein aggregate magnesium-ammonium phospholinoleate-palmitoleate anhydride immuno-modulator (P-MAPA) on canine visceral leishmaniasis. Twenty mongrel dogs ...