RSS 1.0Departamento de Ciências Básicas
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Photomodulation multiple sessions as a promising preventive therapy for medication-related osteonecrosis of the jaws after tooth extraction in rats
Statkievicz, Cristian
; Toro, Luan Felipe ; de Mello-Neto, João Martins ; de Sá, Daniela Pereira ; Casatti, Cláudio Aparecido ; ; Cintra, Luciano Tavares Angelo ; de Almeida, Juliano Milanezi ; Nagata, Maria José Hitomi ; Garcia, Valdir Gouveia et al. (Journal of Photochemistry and Photobiology B: Biology, 2018) [Artigo]
The aim of this study was to evaluate the effects of photobiomodulation (PBM) with multiple sessions of low-level laser on the alveolar repair process of rats with major risk factors for medication-related osteonecrosis ... -
Periodontal disease severity in subjects with dementia: A systematic review and meta-analysis
Gusman, David Jonathan R.; Mello-Neto, João M. ; Alves, Breno Edson S. ; Matheus, Henrique R. ; Ervolino, Edilson ; Theodoro, Letícia H. ; de Almeida, Juliano M. (Archives of Gerontology and Geriatrics, 2018) [Resenha]
Background and objective: Despite clinical trials and reviews attempt to assess a possible relationship between dementia and periodontal disease, no meta-analysis has been performed and this issue remains undetermined. The ... -
Model of hindlimb unloading in adult female rats: Characterizing bone physicochemical, microstructural, and biomechanical properties
Peres-Ueno, Melise Jacon; Stringhetta-Garcia, Camila Tami ; ; ; Chaves-Neto, Antônio Hernandes ; Dornelles, Rita Cássia Menegati ; Louzada, Mário Jefferson Quirino (PLoS ONE, 2017) [Artigo]
Prolonged bedrest and microgravity induce alterations to bone, leading to bone fragility and compromising the quality of life. In this study, we characterized the physicochemical changes, microstructure, and biomechanics ... -
Cisplatin chemotherapy impairs the peri-implant bone repair around titanium implants: An in vivo study in rats
Matheus, Henrique Rinaldi; Ervolino, Edilson ; Faleiros, Paula Lazilha ; Novaes, Vivian Cristina Noronha ; Theodoro, Leticia Helena ; Garcia, Valdir Gouveia ; de Almeida, Juliano Milanezi (Journal of Clinical Periodontology, 2018) [Artigo]
Aim: The purpose of this study in animals was to evaluate the peri-implant bone repair against systemic administration of the antineoplastic agent. Material and methods: We used 84 male rats (Rattus norvegicus, albinus, ... -
Effects of strength training and raloxifene on femoral neck metabolism and microarchitecture of aging female Wistar rats
; ; ; ; ; ; Chaves-Neto, Antonio Hernandes; Ervolino, Edilson ; Dornelles, Rita Cássia Menegati (Scientific Reports, 2017) [Artigo]
The aim of this study was to prevent female osteoporosis using strength training (ST), raloxifene (Ral) or a combination of ST plus Ral during the natural female aging process, specifically in the periestropause period. ... -
Endodontic infections increase leukocyte and lymphocyte levels in the blood
Samuel, Renata Oliveira; Gomes-Filho, João Eduardo ; Azuma, Mariane Maffei ; Sumida, Dóris Hissako ; de Oliveira, Sandra Helena Penha ; Chiba, Fernando Yamamoto ; Bomfim, Suely Regina Mogami ; Ciarlini, Paulo César ; Narciso, Luis Gustavo ; Cintra, Luciano Tavares Angelo (Clinical Oral Investigations, 2018) [Artigo]
Objectives: The aim of this study was to determine whether the presence of single or multiple apical periodontitis (AP) alters blood cell counts and cytokine production. Material and methods: Thirty rats were divided into ... -
Influence of obesity on experimental periodontitis in rats: histopathological, histometric and immunohistochemical study
; Garcia, Valdir Gouveia; Theodoro, Letícia Helena ; Ervolino, Edilson ; ; Longo, Mariéllen ; ; ; Spolidorio, Luís Carlos ; Zuanon, José Antônio Sampaio et al. (Clinical Oral Investigations, 2018) [Artigo]
Objectives: This study assessed the influence of obesity on the progression of ligature-induced periodontitis in rats. Materials and methods: Forty-eight adult Wistar rats were randomly divided into two groups: the HL group ... -
RANK/RANKL/OPG expression in rapid maxillary expansion
; ; ; ; Ervolino, Edilson; (Brazilian Dental Journal, 2017) [Artigo]
The aim of this study was to evaluate osteoclastogenesis signaling in midpalatal suture after rapid maxillary expansion (RME) in rats. Thirty male Wistar rats were randomly assigned to two groups with 15 animals each: ... -
Histomorphometric and immunohistochemical assessment of RUNX2 and VEGF of Biogran™ and autogenous bone graft in human maxillary sinus bone augmentation: A prospective and randomized study
Pereira, Rodrigo dos Santos; Menezes, Juliana Dreyer ; Bonardi, João Paulo ; Griza, Geraldo Luiz ; Okamoto, Roberta ; Hochuli-Vieira, Eduardo (Clinical Implant Dentistry and Related Research, 2017) [Artigo]
Background: Few studies have been conducted to assess new bone formation using Biogran, a bioactive glass, in maxillary sinus bone augmentation through a prospective and randomized evaluation. Moreover, there are no studies ... -
Hydrogen peroxide induces cell proliferation and apoptosis in pulp of rats after dental bleaching in vivo: Effects of the dental bleaching in pulp
Benetti, Francine; Gomes-Filho, João Eduardo ; Ferreira, Luciana Louzada ; Ervolino, Edilson ; Briso, André Luiz Fraga ; Sivieri-Araújo, Gustavo ; Dezan-Júnior, Eloi ; Cintra, Luciano Tavares Angelo (Archives of Oral Biology, 2017) [Artigo]
Objective This study provides an in vivo evaluation of the inflammatory response, levels of cell proliferation and apoptosis, and the presence of necrosis after dental bleaching with two concentrations of hydrogen peroxide ... -
Low-level laser and antimicrobial photodynamic therapy on experimental periodontitis in rats submitted to chemotherapy by 5-fluorouracil
Theodoro, Leticia Helena; Longo, Mariéllen ; Novaes, Vivian Cristina Noronha ; Miessi, Daniela Maria Janjacomo ; Ferro-Alves, Marcio Luiz ; Ervolino, Edilson ; de Almeida, Juliano Milanezi ; Garcia, Valdir Gouveia (Supportive Care in Cancer, 2017) [Artigo]
Purpose: The aim of this study was to evaluate the effects of low-level laser therapy (LLLT) and antimicrobial photodynamic therapy (aPDT) as adjuvant to mechanical treatment of experimental periodontitis (EP) in adult ... -
Periapical Lesions Increase Macrophage Infiltration and Inflammatory Signaling in Muscle Tissue of Rats
Pereira, Renato Felipe; Cintra, Luciano Tavares Angelo ; Tessarin, Gestter Willian Lattari ; Chiba, Fernando Yamamoto ; de Lima Coutinho Mattera, Maria Sara ; Scaramele, Natalia Francisco ; Tsosura, Thais Verônica Saori ; Ervolino, Edilson ; de Oliveira, Sandra Helena Penha ; Sumida, Doris Hissako (Journal of Endodontics, 2017) [Artigo]
Introduction Our previous studies have shown that periapical lesions (PLs) in rats cause systemic disorders such as increased tumor necrosis factor-α plasma levels, insulin resistance, and impairment in insulin signal ... -
Raloxifene but not alendronate can compensate the impaired osseointegration in osteoporotic rats
Faverani, Leonardo Perez; Polo, Tárik Ocon Braga ; Ramalho-Ferreira, Gabriel ; Momesso, Gustavo Antonio Correa ; Hassumi, Jaqueline Suemi ; ; ; ; Luvizuto, Eloá Rodrigues ; et al. (Clinical Oral Investigations, 2018) [Artigo]
Objectives: Alendronate and raloxifene, a bisphosphonate and a selective estrogen modulator, respectively, are established osteoporosis therapies. Current evidence suggests that simultaneous application of osteoporosis ... -
Aged rats under zoledronic acid therapy and oral surgery
Matsumoto, Mariza Akemi; de Abreu Furquim, Elisa Mara ; Gonçalves, Alaíde ; ; ; ; ; Okamoto, Roberta (Journal of Cranio-Maxillofacial Surgery, 2017) [Artigo]
Introduction Aging brings a number of health conditions that can compromise the healing process in elderly individuals, significantly when it comes to bone tissue. The aim of the present study was to analyze the effects ... -
Immunohistochemical response in rats of beta-tricalcium phosphate (TCP) with or without BMP-2 in the production of collagen matrix critical defects
Luvizuto, Eloá Rodrigues; de Oliveira, Júlio César Silva ; Gomes-Ferreira, Pedro Henrique Silva ; Pereira, Cassiano Costa Silva ; Faverani, Leonardo Perez ; Antoniali, Cristina ; Okamoto, Roberta (Acta Histochemica, 2017) [Artigo]
This study aimed to assess the biological response of BMP-2 (bone morphogenetic protein-2) in supplementation with β-tricalcium phosphate (TCP) as a carrier in the bone healing of surgical defects in rats’ calvaria. A ... -
Effects of strength training on osteogenic differentiation and bone strength in aging female Wistar rats
; ; ; ; Louzada, Mário Jefferson Quirino; Oliveira, Sandra Helena Penha ; Chaves Neto, Antonio Hernandes ; Dornelles, Rita Cássia Menegati (Scientific Reports, 2017) [Artigo]
The effects of strength training (ST) on the mechanical bone strength and osteogenic differentiation of bone marrow mesenchymal stromal cells (BMSCs) from adult, aged and exercised aged rats were determined. The exercised ... -
Low-level laser therapy stimulates bone metabolism and inhibits root resorption during tooth movement in a rodent model
; ; ; Ervolino, Edilson; ; (Journal of Biophotonics, 2016) [Artigo]
This study evaluated the biological effects of low-level laser therapy (LLLT) on bone remodeling, tooth displacement and root resorption, occurred during the orthodontic tooth movement. Upper first molars of a total of ... -
Sodium and water intake are not affected by GABAC receptor activation in the lateral parabrachial nucleus of sodium-depleted rats
; ; ; Callera, João Carlos; (Journal of Chemical Neuroanatomy, 2016) [Artigo]
The activation of GABAergic receptors, GABAA and GABAB, in the lateral parabrachial nucleus (LPBN) increases water and sodium intake in satiated and fluid-depleted rats. The present study investigated the presence of the ... -
Evaluation of an experimental rat model for comparative studies of bleaching agents
Cintra, Luciano Tavares Angelo; Benetti, Francine ; Ferreira, Luciana Lousada ; Rahal, Vanessa ; Ervolino, Edilson ; De Castilho Jacinto, Rogério ; Gomes Filho, Joäo Eduardo ; Briso, Andre Luiz Fraga (Journal of Applied Oral Science, 2016) [Artigo]
Dental materials, in general, are tested in different animal models prior to their clinical use in humans, except for bleaching agents. Objectives: To evaluate an experimental rat model for comparative studies of bleaching ... -
Antimicrobial photodynamic therapy minimizes the deleterious effect of nicotine in female rats with induced periodontitis
Gualberto, Erivan Clementino; Theodoro, Letícia Helena ; Longo, Mariellén ; Novaes, Vivian Cristina Noronha ; Nagata, Maria José Hitomi ; Ervolino, Edilson ; Garcia, Valdir Gouveia (Lasers in Medical Science, 2016) [Artigo]
The aim of this study was to compare the use of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) in the treatment of experimentally induced periodontitis in female rats that were ...