Effect of fluoride intake on carbohydrate metabolism, glucose tolerance, and insulin signaling
Abstract
Fluoride is known to cause both local and systemic alterations in animals and humans, such as dental fluorosis and disturbances in glucose homeostasis. The effects of fluoride are dose dependent and can produce decreased insulin secretion, inhibition of glycolysis, glycogen depletion, hyperglycemia, and insulin resistance. Because excessive ingestion of fluoride during tooth brushing can lead to deterioration in health, the use of low-fluoride dentifrices is recommended for young children with diabetes.
How to cite this document
Chiba, Fernando Yamamoto; Garbin, Clea Adas Saliba; Sumida, Doris Hissako. Effect of fluoride intake on carbohydrate metabolism, glucose tolerance, and insulin signaling. Fluoride. Ocean View: Int Soc Fluoride Research, v. 45, n. 3, p. 236-241, 2012. Available at: <http://hdl.handle.net/11449/14970>.
Keywords
Language
English
Sponsor
Pró-Reitoria de Pesquisa da UNESP (PROPe UNESP)
Fundação para o Desenvolvimento da UNESP (FUNDUNESP)
