Now showing items 1-10 of 93
Antihypertensive responses elicited by central moxonidine in rats: Possible role of nitric oxide
(Journal of Cardiovascular Pharmacology, 2006-06-01) [Artigo]
In the present study, we investigated the effects of pretreatment with N-G-nitro-L-arginine methyl ester (L-NAME) (nitric oxide synthase inhibitor) injected intravenously (IV) on the hypotension, bradycardia, and vasodilation ...
Alpha(2)-adrenergic activation in the lateral parabrachial nucleus induces NaCi intake under conditions of systemic hyperosmolarity
(Neuroscience, 2006-09-29) [Artigo]
The inhibition of sodium intake by increased plasma osmolarity may depend on inhibitory mechanisms present in the lateral parabrachial nucleus. Activation of alpha(2)-adrenergic receptors in the lateral parabrachial nucleus ...
The bradycardic and hypotensive responses to serotonin are reduced by activation of GABA A receptors in the nucleus tractus solitarius of awake rats
(Brazilian Journal of Medical and Biological Research, 2005-07-01) [Artigo]
We investigated the effects of bilateral injections of the GABA receptor agonists muscimol (GABA A) and baclofen (GABA B) into the nucleus tractus solitarius (NTS) on the bradycardia and hypotension induced by iv serotonin ...
Lesions of the commissural subnucleus of the nucleus of the solitary tract increase isoproterenol-induced water intake
(Brazilian Journal of Medical and Biological Research, 2007-08-01) [Artigo]
The nucleus of the solitary tract (NTS) is the primary site of the cardiovascular afferent information about arterial blood pressure and volume. The NTS projects to areas in the central nervous system involved in cardiovascular ...
Moxonidine reduces pilocarpine-induced salivation in rats
(Autonomic Neuroscience-basic & Clinical, 2001-08-13) [Artigo]
Cholinergic, agonists activate salivation and the alpha (2)-adrenergic and imidazoline receptor agonists induce opposite effects. In the present study, we investigated the effects of intracerebroventricular (i.c.v.) or ...
Moxonidine and central alpha(2) adrenergic receptors in sodium intake
(Brain Research, 2003-12-12) [Artigo]
Central injections of the alpha(2) adrenergic/imidazoline receptor agonist moxonidine inhibit water and NaCl intake in rats. In the present study, we investigated the possible involvement of central alpha(2) adrenergic ...
Vasopressin-dependent pressor responses induced by hypertonic saline load in rats with commissural NTS lesions
(FASEB Journal, 2007-04-01) [Resumo]
Effects of central imidazolinergic and alpha2-adrenergic activation on water intake
(Brazilian Journal of Medical and Biological Research, 2001-09-01) [Artigo]
Non-adrenergic ligands that bind to imidazoline receptors (I-R), a selective ligand that binds to alpha2-adrenoceptors (alpha2-AR) and mixed ligands that bind to both receptors were tested for their action on water intake ...
Episodes of water deprivation enhance daily hypertonic NaCl intake in rats
(Brazilian Journal of Medical and Biological Research, 2002-04-01) [Artigo]
Water and 1.8% NaCl intake was recorded daily in adult male rats (N = 6) submitted to four water deprivations plus four sodium appetite tests, each at the end of each 7-day interval, or in controls (non-deprived, N = 6). ...