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dc.contributor.authorLopes Novato, Tatiane Pinheiro
dc.contributor.authorAraujo, Laryssa Xavier
dc.contributor.authorOliveira de Monteiro, Caio Marcio
dc.contributor.authorMaturano, Ralph
dc.contributor.authorSouza Senra, Tatiane de Oliveira
dc.contributor.authorMatos, Renata da Silva [UNESP]
dc.contributor.authorGomes, Geovany Amorim
dc.contributor.authorCarvalho, Mario Geraldo de
dc.contributor.authorDaemon, Erik
dc.identifier.citationVeterinary Parasitology. Amsterdam: Elsevier Science Bv, v. 212, n. 3-4, p. 331-335, 2015.
dc.description.abstractThis study aimed at assessing the combined effect of thymol, carvacrol and (E)-cinnamaldehyde on Amblyomma sculptum and Dermacentor nitens larvae. The effects resulting from treatments were evaluated by means of the modified larval packet test. In order to determine the LC50, components of essential oils, the monoterpenes thymol, carvacrol and phenylpropanoid (E)-cinnamaldehyde were individually tested at different concentrations. After determining the LC50, each essential oil component was separately evaluated and then combined with another substance at a 1:1 proportion at the LC50 concentration and at 1/2 and 1/4 of the LC50. For A. sculptum, the lowest LC50 value was obtained for (E)-cinnamaldehyde (1.40 mg/ml), followed by thymol (2.04 mg/ml) and carvacrol (3.49 mg/ml). The same order of effectiveness was observed for D. nitens, with values of 1.68, 2.17 and 3.33 mg/ml, respectively. In the evaluation of component associations of essential oils against A. sculptum larvae, only the combinations between carvacrol and thymol (LC50) and carvacrol and (E)-cinnamaldehyde (1/4 LC50) presented a moderate synergetic effect. In turn, for D. nitens larvae, the combinations between thymol and carvacrol (LC50 and 1/2 LC50) presented a synergetic effect, while the others presented an additive or antagonistic effect. Therefore, it can be concluded that the combination of thymol and carvacrol (LC50) has a moderate synergetic effect against A. sculptum larvae, while thymol, combined with carvacrol (LC50 and 1/2 LC50), has a synergetic effect against D. nitens larvae. (C) 2015 Elsevier B.V. All rights reserved.en
dc.publisherElsevier B.V.
dc.relation.ispartofVeterinary Parasitology
dc.sourceWeb of Science
dc.titleEvaluation of the combined effect of thymol, carvacrol and (E)-cinnamaldehyde on Amblyomma sculptum (Acari: Ixodidae) and Dermacentor nitens (Acari: Ixodidae) larvaeen
dcterms.rightsHolderElsevier B.V.
dc.contributor.institutionUniv Fed Juiz de Fora
dc.contributor.institutionUniv Fed Rural Rio de Janeiro
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationUniv Fed Juiz de Fora, Programa Posgrad Comportamento & Biol Anim, BR-36036330 Juiz De Fora, MG, Brazil
dc.description.affiliationUniv Fed Rural Rio de Janeiro, Programa Posgrad Ciencias Vet, Rio De Janeiro, Brazil
dc.description.affiliationUniv Fed Rural Rio de Janeiro, Inst Ciencias Exatas, Dept Quim, Rio De Janeiro, Brazil
dc.description.affiliationUniv Estadual Paulista, Programa Posgrad Biol Celular & Mol, BR-13505470 Sao Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Programa Posgrad Biol Celular & Mol, BR-13505470 Sao Paulo, Brazil
dc.rights.accessRightsAcesso aberto
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