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dc.contributor.authorRosa, F. P.
dc.contributor.authorLia, Raphael Carlos Comelli [UNESP]
dc.contributor.authorde Souza, KOF
dc.contributor.authorGoissis, G.
dc.contributor.authorMarcantonio, E.
dc.date.accessioned2014-02-26T17:14:43Z
dc.date.accessioned2014-05-20T13:45:09Z
dc.date.available2014-02-26T17:14:43Z
dc.date.available2014-05-20T13:45:09Z
dc.date.issued2003-01-01
dc.identifierhttp://dx.doi.org/10.1016/S0142-9612(02)00292-2
dc.identifier.citationBiomaterials. Oxford: Elsevier B.V., v. 24, n. 2, p. 207-212, 2003.
dc.identifier.issn0142-9612
dc.identifier.urihttp://hdl.handle.net/11449/15865
dc.description.abstractThe tissue response to polyanionic collagen matrices, prepared from bovine pericardium and implanted subperiosteally in rat calvaria, was studied. The materials were implanted in 72 male rats (Rattus norvegicus, albinus, Holtzman), randomly divided into four groups: GI-MBP hydrolyzed for 24 h; GII-MBP hydrolyzed for 36 h; GIII-MBP hydrolyzed for 48 h; GIV-native M BP. The materials were explanted after 15, 30 and 60 days and analyzed by routine histological procedures. Except for group IV (native bovine pericardium), polyanionic collagen from groups GI, GII and GIII showed low inflammatory reaction associated with bone formation, partially or completely integrated to the cranial bone; group GIV was characterized by an intense inflammatory reaction with occasional dystrophic mineralization and with occasional bone formation at 60 days when there was a decrease in the inflammatory reaction. Thus, the MBP from groups I, II and III were biologically compatible, enhancing bone formation with a slight delay at 60 days in GII. (C) 2002 Elsevier B.V. Ltd. All rights reserved.en
dc.format.extent207-212
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofBiomaterials
dc.sourceWeb of Science
dc.subjectPolyanionic collagenpt
dc.subjectBiocompatibilitypt
dc.subjectOsteogenesispt
dc.subjectBone substitutept
dc.titleTissue response to polyanionic collagen: elastin matrices implanted in rat calvariaen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.description.affiliationUniv Estadual Paulista, Fac Odontol Araraquara, Dept Diag & Surg, Araraquara, SP, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Odontol, Dept Pathol, BR-14801903 Araraquara, SP, Brazil
dc.description.affiliationUniv São Paulo, Dept Chem Mol Phys, Inst Chem, Sao Carlos, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Odontol Araraquara, Dept Diag & Surg, Araraquara, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Odontol, Dept Pathol, BR-14801903 Araraquara, SP, Brazil
dc.identifier.doi10.1016/S0142-9612(02)00292-2
dc.identifier.wosWOS:000179472000002
dc.rights.accessRightsAcesso restrito
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt
unesp.author.orcid0000-0003-1294-2305[5]
dc.relation.ispartofjcr8.806
dc.relation.ispartofsjr3,111
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