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dc.contributor.authorSaiani, Regina Aparecida
dc.contributor.authorPorto, Isabel Maria
dc.contributor.authorMarcantonio Júnior, Elcio [UNESP]
dc.contributor.authorCury, Jaime Aparecido
dc.contributor.authorde Sousa, Frederico Barbosa
dc.contributor.authorGerlach, Raquel Fernanda
dc.identifier.citationArchives of Oral Biology. Oxford: Pergamon-Elsevier B.V. Ltd, v. 54, n. 11, p. 1008-1015, 2009.
dc.description.abstractThe morphological characterization of fluorotic rat incisor enamel was carried out. Experimental adult animals received drinking water with 45 mg F/L of fluoride, and the control group received distilled water. Fluoride concentrations found in the control and fluorosis groups were 0.04 and 0.09 mu g/mL (plasma), 0.26 and 0.66 mu g/mg (whole tibia), and 0.24 and 2.3 mu g/mg (tibia surface), with P <= 0.001 for all comparisons between the groups. A succession of white and pigmented bands was observed in the fluorotic rat incisors. Under polarizing light microscopy, cross-sections of superficial areas corresponding to the white bands (from the surface to similar to 20 mu m) showed high positive birefringence. These fluorotic lesions also exhibited the lowest resistance to superficial acid etching. No morphological differences in inner enamel were seen under scanning electron microscopy. In fluorotic enamel, only the surface layer related to the white areas presented lower birefiringence compared with the enamel of control teeth and the surface layer of the pigmented areas (normal ones) of fluorotic teeth. In conclusion, the white bands of fluorotic rat enamel represent hypomineralized superficial areas and are not subsurface lesions. The detailed description of these lesions is important to understand dental fluorosis. (C) 2009 Elsevier Ltd. All rights reserved.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.publisherPergamon-Elsevier B.V. Ltd
dc.relation.ispartofArchives of Oral Biology
dc.sourceWeb of Science
dc.subjectPolarized light microscopyen
dc.titleMorphological characterization of rat incisor fluorotic lesionsen
dcterms.rightsHolderPergamon-Elsevier B.V. Ltd
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversidade Federal da Paraíba (UFPB)
dc.description.affiliationFORP USP, Dent Sch Ribeirao Preto, Dept Morfol Estomatol & Fisiol, BR-14040904 Ribeirao Preto, SP, Brazil
dc.description.affiliationFORP USP, Dent Sch Ribeirao Preto, Dept Pediat Clin Prevent & Soc Dent, BR-14040904 Ribeirao Preto, SP, Brazil
dc.description.affiliationFOP UNICAMP, Dent Sch Piracicaba, Dept Morphol, Piracicaba, SP, Brazil
dc.description.affiliationSão Paulo State Univ UNESP, Dent Sch Araraquara, Div Periodont, Dept Diagnost & Surg, Araraquara, SP, Brazil
dc.description.affiliationFOP UNICAMP, Dent Sch Piracicaba, Dept Biochem, Piracicaba, SP, Brazil
dc.description.affiliationUniversidade Federal da Paraíba (UFPB), Hlth Sci Ctr, Dept Morphol, Joao Pessoa, Paraiba, Brazil
dc.description.affiliationUnespSão Paulo State Univ UNESP, Dent Sch Araraquara, Div Periodont, Dept Diagnost & Surg, Araraquara, SP, Brazil
dc.rights.accessRightsAcesso restrito
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Odontologia, Araraquarapt
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