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dc.contributor.authorRosa, Thiago S.
dc.contributor.authorSimoes, Herbert G.
dc.contributor.authorRogero, Marcelo M.
dc.contributor.authorMoraes, Milton R.
dc.contributor.authorDenadai, Benedito S. [UNESP]
dc.contributor.authorArida, Ricardo M.
dc.contributor.authorAndrade, Marilia S.
dc.contributor.authorSilva, Bruno M.
dc.date.accessioned2018-11-26T16:32:44Z
dc.date.available2018-11-26T16:32:44Z
dc.date.issued2016-04-19
dc.identifierhttp://dx.doi.org/10.3389/fphys.2016.00122
dc.identifier.citationFrontiers In Physiology. Lausanne: Frontiers Media Sa, v. 7, 10 p., 2016.
dc.identifier.issn1664-042X
dc.identifier.urihttp://hdl.handle.net/11449/161432
dc.description.abstractSevere obesity affects metabolism with potential to influence the lactate and glycemic response to different exercise intensities in untrained and trained rats. Here we evaluated metabolic thresholds and maximal aerobic capacity in rats with severe obesity and lean counterparts at pre- and post-training. Zucker rats (obese: n = 10, lean: n = 10) were submitted to constant treadmill bouts, to determine the maximal lactate steady state, and an incremental treadmill test, to determine the lactate threshold, glycemic threshold and maximal velocity at pre and post 8 weeks of treadmill training. Velocities of the lactate threshold and glycemic threshold agreed with the maximal lactate steady state velocity on most comparisons. The maximal lactate steady state velocity occurred at higher percentage of the maximal velocity in Zucker rats at pre-training than the percentage commonly reported and used for training prescription for other rat strains (i.e., 60%) (obese = 78 +/- 9% and lean = 68 +/- 5%, P < 0.05 vs. 60%). The maximal lactate steady state velocity and maximal velocity were lower in the obese group at pre-training (P < 0.05 vs. lean), increased in both groups at post-training (P < 0.05 vs. pre), but were still lower in the obese group at post-training (P < 0.05 vs. lean). Training-induced increase in maximal lactate steady state, lactate threshold and glycemic threshold velocities was similar between groups (P > 0.05), whereas increase in maximal velocity was greater in the obese group (P < 0.05 vs. lean). In conclusion, lactate threshold, glycemic threshold and maximal lactate steady state occurred at similar exercise intensity in Zucker rats at pre- and post-training. Severe obesity shifted metabolic thresholds to higher exercise intensity at pre-training, but did not attenuate submaximal and maximal aerobic training adaptations.en
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent10
dc.language.isoeng
dc.publisherFrontiers Media Sa
dc.relation.ispartofFrontiers In Physiology
dc.sourceWeb of Science
dc.subjectaerobic capacity
dc.subjectexercise training
dc.subjectdiabetes
dc.subjectobesity
dc.subjectmaximal lactate steady state
dc.subjectincremental test
dc.titleSevere Obesity Shifts Metabolic Thresholds but Does Not Attenuate Aerobic Training Adaptations in Zucker Ratsen
dc.typeArtigo
dcterms.rightsHolderFrontiers Media Sa
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Catolica Brasilia
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationUniv Fed Sao Paulo, Grad Program Translat Med, Sao Paulo, Brazil
dc.description.affiliationUniv Catolica Brasilia, Grad Program Phys Educ & Hlth, Brasilia, DF, Brazil
dc.description.affiliationUniv Sao Paulo, Sch Publ Hlth, Dept Nutr, Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Nephrol, Sao Paulo, Brazil
dc.description.affiliationSao Paulo State Univ, Dept Phys Educ, Human Performance Lab, Rio Claro, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Physiol, Sao Paulo, Brazil
dc.description.affiliationUnespSao Paulo State Univ, Dept Phys Educ, Human Performance Lab, Rio Claro, Brazil
dc.identifier.doi10.3389/fphys.2016.00122
dc.identifier.wosWOS:000374450800001
dc.rights.accessRightsAcesso aberto
dc.identifier.fileWOS000374450800001.pdf
unesp.author.lattes1907479250833033[5]
unesp.author.orcid0000-0003-0775-1889[5]
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