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dc.contributor.authorSteffens, Joao Paulo [UNESP]
dc.contributor.authorSantos, Fabio Andre
dc.contributor.authorPilatti, Gibson Luiz
dc.identifier.citationAmerican Journal of Dentistry. Weston: Mosher & Linder, Inc, v. 24, n. 6, p. 354-356, 2011.
dc.description.abstractPurpose: To assess and compare the efficacy of two different dexamethasone protocols on pain prevention following periodontal surgery. Methods: 60 subjects presenting moderate to severe periodontitis with persisting clinical signs of inflammation after nonsurgical periodontal therapy on at least two adjacent teeth were scheduled for open flap debridement surgeries. This was a double-blind, parallel-group, placebo-controlled randomized clinical trial. Each patient was randomly assigned to receive one of the following preoperative medication protocols, 1 hour before surgery: Protocol 1 (P1): 4 mg dexamethasone, and another 4 mg 8 hours after the first dose; P2: 8 mg dexamethasone; P3: placebo. Pain intensity was evaluated hourly for the first 8 hours after surgery using the visual analogue scale (VAS). For ethical reasons, patients were instructed to use acetaminophen 750 mg as a rescue medication, only in case of pain. Results: P2 demonstrated to be more effective than P3 at all time periods, except for the 2nd hour. P2 was also superior to P1 at 1-(Kruskal-Wallis; P= 0.034), 5- (P= 0.03), 6- (P=0.04), 7- (P= 0.005) and 8-hour (P= 0.01) periods. The need for rescue medication was significantly prevented when P2 was used (ANOVA; P= 0.02). (Am J Dent 2011;24:354-356).en
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.publisherMosher & Linder, Inc
dc.relation.ispartofAmerican Journal of Dentistry
dc.sourceWeb of Science
dc.titlePostoperative periodontal pain prevention using two dexamethasone medication protocols: A double-blind, parallel-group, placebo-controlled randomized clinical trialen
dcterms.rightsHolderMosher & Linder, Inc
dc.contributor.institutionUniversidade Estadual de Ponta Grossa (UEPG)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.description.affiliationUniversidade Estadual de Ponta Grossa (UEPG), Dent Postgrad Program, Ponta Grossa, PR USA
dc.description.affiliationUNESP Univ Estadual Paulista, Dept Physiol & Pathol, Araraquara Dent Sch, São Paulo, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Dept Physiol & Pathol, Araraquara Dent Sch, São Paulo, Brazil
dc.rights.accessRightsAcesso restrito
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt[1]
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