RSS 1.0Departamento de Morfologia
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The influence of Cisplatin-based chemotherapy on the osseointegration of dental implants: An in vivo mechanical and histometrical study
Dantas, Marcos Vinícius Mendes
; Verzola, Mário Henrique Arruda ; Sanitá, Paula Volpato ; Dovigo, Lívia Nordi ; Cerri, Paulo Sérgio ; Gabrielli, Marisa Aparecida Cabrini (Clinical Oral Implants Research, 2019) [Artigo]
Objectives: To evaluate the effect of Cisplatin on bone repair and mineralization around implants and on the mechanical properties of bone tissue. Materials and methods: Forty-three Wistar rats were randomly divided into ... -
Systemic expression of genes related to inflammation and lipid metabolism in patients with dyslipidemia, type 2 diabetes mellitus and chronic periodontitis
Nepomuceno, Rafael; Vallerini, Bruna de F. ; da Silva, Romerito L. ; Corbi, Sâmia C.T. ; Bastos, Alliny de S. ; ; ; Regina P Orrico, Silvana ; Scarel-Caminaga, Raquel M. (Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 2019) [Artigo]
Inflammatory diseases, as periodontal disease (PD), has been associated with disturbance of lipid and glycemic metabolisms, as demonstrated by the increasing of PD patients with type 2 diabetes mellitus (T2D) and/or ... -
Periodontal status of individuals with Down syndrome: sociodemographic, behavioural and family perception influence
Nuernberg, M. A.A.; Ivanaga, C. A. ; ; Aranega, A. M. ; ; Caminaga, R. M.S. ; ; Theodoro, L. H. (Journal of Intellectual Disability Research, 2019) [Artigo]
Background: The aim of the present study was to assess the periodontal condition of individuals with Down syndrome and the association with sociodemographic and behavioural characteristics and family perception of oral ... -
Genes Regulating Immune Response and Amelogenesis Interact in Increasing the Susceptibility to Molar-Incisor Hypomineralization
Bussaneli, Diego Girotto; ; Fragelli, Camila Maria Bullio ; Santos-Pinto, Lourdes ; Jeremias, Fabiano ; Cordeiro, Rita De Cássia Loiola ; ; ; Scarel-Caminaga, Raquel Mantuaneli (Caries Research, 2019) [Artigo]
Ameloblasts are sensitive cells whose metabolism and function may be affected by inflammatory stimuli. The aim of this study was to evaluate the possible association between polymorphisms in immune response-related genes ... -
Functionality of the Interleukin 8 haplotypes in lymphocytes and macrophages in response to gram-negative periodontopathogens
Pigossi, Suzane C.; Anovazzi, Giovana ; Finoti, Livia S. ; de Medeiros, Marcell C. ; ; Rossa Junior, Carlos ; Scarel-Caminaga, Raquel M. (Gene, 2019) [Artigo]
Individuals carrying the ATC/TTC haplotype (Hap-1) in the interleukin 8 (IL8) gene were reported as more susceptible to chronic periodontitis (CP), an infectious disease associated with Gram-negative bacteria, in comparison ... -
Matrix Metalloproteinase-1 and Acid Phosphatase in the Degradation of the Lamina Propria of Eruptive Pathway of Rat Molars
; Sasso-Cerri, Estela; Cerri, Paulo Sergio (Cells, 2018) [Artigo]
The comprehension of dental pathogenesis and disorders derived from eruption failure requires a deep understanding of the molecular mechanisms underlying normal tooth eruption. As intense remodelling is needed during tooth ... -
Fluoxetine-induced androgenic failure impairs the seminiferous tubules integrity and increases ubiquitin carboxyl-terminal hydrolase L1 (UCHL1): Possible androgenic control of UCHL1 in germ cell death?
Camara, Marina L.; Almeida, Talita B. ; ; Rodrigues, Beatriz M. ; Cerri, Paulo S. ; ; Sasso-Cerri, Estela (Biomedicine & Pharmacotherapy, 2019) [Artigo]
The selective serotonin reuptake inhibitor fluoxetine has been used for the treatment of depression. Although sexual disorders have been reported in male patients, few studies have demonstrated the fluoxetine effect on the ... -
VEGF immunoexpression related to the ectomesenchymal cells differentiation into osteoblasts during early development of alveolar process in rat molars.
; ; Sasso-Cerri, E.; ; Cerri, P. S. (Molecular Biology Of The Cell, 2014) [Resumo]
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Estrogen improves osteocyte viability by inhibiting apoptosis and enhancing autophagy in alveolar process of ovariectomized rats.
; ; Sasso-Cerri, E.; ; Cerri, P. S. (Molecular Biology Of The Cell, 2014) [Resumo]
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Antimicrobial photodynamic therapy mediated by curcumin-loaded polymeric nanoparticles in a murine model of oral candidiasis
Sakima, Vinicius Tatsuyuji; Barbugli, Paula Aboud ; Cerri, Paulo Sérgio ; Chorilli, Marlus ; Carmello, Juliana Cabrini ; Pavarina, Ana Cláudia ; De Oliveira Mima, Ewerton Garcia (Molecules, 2018) [Artigo]
Antimicrobial photodynamic therapy (aPDT) has been proposed as an alternative method for oral candidiasis (OC), while nanocarriers have been used to improve the water solubility of curcumin (CUR). The aim of this study is ... -
Bonefill® block as alternative for bone substitute: A toxicological evaluation
Melchior, Karine; Saska, Sybele ; Coelho, Fernanda ; Scarel-Caminaga, Raquel Mantuaneli ; Capote, Ticiana Sidorenko de Oliveira (Brazilian Journal of Pharmaceutical Sciences, 2018) [Artigo]
Bone substitutes based on hydroxyapatite (HA) and Bonefill® (BO-inorganic bovine bone) associated with poly(lactic-co-glycolic acid) (PLGA) (HA/PLGA and BO/PLGA) were evaluated concerning cytotoxicity, genotoxicity and ... -
Discovery of phenylsulfonylfuroxan derivatives as gamma globin inducers by histone acetylation
Melo, Thais Regina Ferreira de; ; Fernandes, Guilherme Felipe Dos Santos ; ; Chelucci, Rafael Consolin ; Barbieri, Karina Pereira ; Coelho, Fernanda ; Capote, Ticiana Sidorenko de Oliveira ; ; Carlos, Iracilda Zeppone et al. (European journal of medicinal chemistry, 2018) [Artigo]
N-oxide derivatives 5(a-b), 8(a-b), and 11(a-c) were designed, synthesized and evaluated in vitro and in vivo as potential drugs that are able to ameliorate sickle cell disease (SCD) symptoms. All of the compounds demonstrated ... -
Biodentine and MTA modulate immunoinflammatory response favoring bone formation in sealing of furcation perforations in rat molars
da Fonseca, Tiago Silva; ; Guerreiro-Tanomaru, Juliane M. ; Delfino, Mateus Machado ; Sasso-Cerri, Estela ; Tanomaru-Filho, Mário ; Cerri, Paulo Sérgio (Clinical Oral Investigations, 2018) [Artigo]
Objectives: Evaluate the tissue reaction of periodontium subjacent to furcation perforations in rat molars sealed with Biodentine or mineral trioxide aggregate (MTA). Materials and methods: The pulp chamber floor of right ... -
Biopolymer-based membranes associated with osteogenic growth peptide for guided bone regeneration
Saska, Sybele; Pigossi, Suzane C ; Oliveira, Guilherme J. P. L. ; ; Capela, Marisa V. ; Gonçalves, Andreia ; ; Messaddeq, Younès ; Ribeiro, Sidney J. L. ; Gaspar, Ana Maria Minarelli et al. (Biomedical Materials (Bristol), 2018) [Artigo]
Barrier membranes for guided bone regeneration (GBR) mainly promote mechanical maintenance of bone defect space and induce osteopromotion. Additionally, biopolymer-based membranes may provide greater bioactivity and ... -
Reduced interleukin-6 immunoexpression and birefringent collagen formation indicate that MTA Plus and MTA Fillapex are biocompatible
Saraiva, Juliana Alcarás; Da Fonseca, Tiago Silva ; Da Silva, Guilherme Ferreira ; Sasso-Cerri, Estela ; Guerreiro-Tanomaru, Juliane Maria ; Tanomaru-Filho, Mario ; Cerri, Paulo Sérgio (Biomedical Materials (Bristol), 2018) [Artigo]
Considering that endodontic sealers release some components which may promote delay in the repair process, our purpose was to evaluate the tissue reaction promoted by MTA Plus and MTA Fillapex in comparison with AH Plus ... -
Differential effects of natural Curcumin and chemically modified curcumin on inflammation and bone resorption in model of experimental periodontitis
; ; Oliveira, Priscilla Aparecida; Cerri, Paulo Sérgio ; ; ; ; ; ; (Archives of Oral Biology, 2018) [Artigo]
Objective: The purpose of this study was to compare the effects of the oral administration of natural curcumin and a chemically modified curcumin (CMC2.24) on osteoclast-mediated bone resorption, apoptosis, and inflammation ... -
Development of coverage and its evaluation in the treatment of chronic wounds
Zanoti, Marcia Diana Umebayashi; ; Ribeiro, Sidney José Lima ; Gaspar, Ana Maria Minarelli (Investigacion y Educacion en Enfermeria, 2017) [Artigo]
Objective. To describe the development of the bacterial cellulose coating with anti-inflammatory Ibuprofen (BC/ Ibu) and to evaluate the cicatrization process with its use in patients with chronic wounds of venous and ... -
Avaliação da toxicidade do cimento ósseo β-TCP/MCPM injetável associado à sílica mesoporosa e peptídeo regulador do crescimento ósseo (OGP) em células CHO-K1
Coelho, Fernanda; Mendes, Larissa ; Saska, Sybele ; Scarel-Caminaga, Raquel Manuanelli ; Marchetto, Reinaldo ; Gaspar, Ana Maria Minarelli ; Rodríguez, Miguel ; De Oliveira Capote, Ticiana Sidorenko (Revista de Ciencias Farmaceuticas Basica e Aplicada, 2017) [Nota]
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Nanocellulose-collagen-apatite composite associated with osteogenic growth peptide bone regeneration
Saska, Sybele; ; ; Scarel-Caminaga, Raquel Mantuaneli ; ; ; Santagneli, Silvia Helena ; Capela, Marisa Veiga ; ; et al. (International Journal of Biological Macromolecules, 2017) [Artigo]
Despite advances in the field of biomaterials for bone repair/regeneration, some challenges for developing an ideal bone substitute need to be overcome. Herein, this study synthesized and evaluated in vitro a nanocomposite ... -
Seminiferous epithelium damage after short period of busulphan treatment in adult rats and vitamin B12 efficacy in the recovery of spermatogonial germ cells
Vasiliausha, Sandi Regina; ; ; Cerri, Paulo Sérgio ; ; Sasso-Cerri, Estela (International Journal of Experimental Pathology, 2016) [Artigo]
Several different strategies have been adopted in attempt to recover from chemotherapy-damaged spermatogenesis that is often seen in oncologic patients. In this study, we have evaluated the impact of short period of exposure ...