Departamento de Morfologia
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Recent Submissions
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Immunoinflammatory response and bioactive potential of GuttaFlow bioseal and MTA Fillapex in the rat subcutaneous tissue
(Scientific Reports, 2020) [Artigo]To evaluate the effect of GuttaFlow bioseal (GFB) and MTA Fillapex (MTAF) in comparison with Endofill (EF) in the subcutaneous tissue. Polyethylene tubes with GFB, MTAF, EF or empty tubes (control group; CG) were implanted ... -
Physical properties, antimicrobial activity and in vivo tissue response to apexit plus
(Materials, 2020) [Artigo]We investigated the physical properties, antimicrobial activity, and tissue reaction to Apexit Plus in comparison to Sealapex. Flow, radiopacity, setting time, and solubility were evaluated in each material. The antimicrobial ... -
Aesthetic perception in children with molar incisor hypomineralization
(European Archives of Paediatric Dentistry, 2020) [Artigo]Purpose: To investigate the relationship between aesthetic perception and molar incisor hypomineralization (MIH) in schoolchildren aged 8–12 years. Methods: The study included 467 pupils enrolled in elementary schools. ... -
Epigenetic reprogramming in periodontal disease: Dynamic crosstalk with potential impact in oncogenesis
(Periodontology 2000, 2020) [Resenha]Periodontitis is a chronic multifactorial inflammatory disease associated with microbial dysbiosis and characterized by progressive destruction of the periodontal tissues. Such chronic infectious inflammatory disease is ... -
Severe magnesium deficiency compromises systemic bone mineral density and aggravates inflammatory bone resorption
(Journal of Nutritional Biochemistry, 2020) [Artigo]We sought to evaluate the effects of magnesium (Mg) intake deficiency on bone metabolism in rats with induced periodontal disease (PD). Holtzman rats were randomly divided into two groups: Control — animals fed a standard ... -
Silk fibroin/hydroxyapatite composite membranes: Production, characterization and toxicity evaluation
(Toxicology in Vitro, 2020) [Artigo]Alloplastic materials based on biopolymers such as silk fibroin (SF) have provided the synthesis of excellent biomaterials for bone repair. The aim of the present study was to produce SF membranes associated to hydroxyapatite ... -
The ATC/TTC haplotype in the Interleukin 8 gene in response to Gram-negative bacteria: A pilot study
(Archives of Oral Biology, 2019) [Artigo]Objective: The aim of this study was to investigate the functionality of ATC/TTC (Hap-1) and ATT/TTC (Hap-2) Interleukin (IL) 8 gene haplotypes in the response of neutrophils to Gram-negative bacteria associated with ... -
Cimetidine-induced vascular cell apoptosis impairs testicular microvasculature in adult rats
(Histology And Histopathology, 2012) [Artigo]Cimetidine, an H-2 receptor antagonist used for treatment of gastric ulcers, exerts antiandrogenic and antiangiogenic effects. In the testes cimetidine impairs spermatogenesis, Sertoli cells and peritubular tissue, inducing ... -
Effects of Continuous and Pulsed Infrared Laser Application on Bone Repair Using Different Energy Doses. Study in Rats
(Proceedings Of The International Conference Of The World Association Of Laser Therapy, 2008) [Trabalho apresentado em evento]The Laser Therapy effects on the cellular proliferation are extensively searched and widely known. However, there are controversies on the best Out put power used in the applications, the ideal fluency and irradiance, ... -
Cimetidine reduces RANKL/OPG ratio and IL-6 immunoexpression in the gingival lamina propria of rat molars with induced periodontal disease
(Molecular Biology Of The Cell, 2013) [Resumo] -
Apoptosis and MMP-1 during the establishment of the eruptive pathway in rat molars
(Molecular Biology Of The Cell, 2013) [Resumo] -
The influence of Cisplatin-based chemotherapy on the osseointegration of dental implants: An in vivo mechanical and histometrical study
(Clinical Oral Implants Research, 2019) [Artigo]Objectives: To evaluate the effect of Cisplatin on bone repair and mineralization around implants and on the mechanical properties of bone tissue. Materials and methods: Forty-three Wistar rats were randomly divided into ... -
Systemic expression of genes related to inflammation and lipid metabolism in patients with dyslipidemia, type 2 diabetes mellitus and chronic periodontitis
(Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 2019) [Artigo]Inflammatory diseases, as periodontal disease (PD), has been associated with disturbance of lipid and glycemic metabolisms, as demonstrated by the increasing of PD patients with type 2 diabetes mellitus (T2D) and/or ... -
Periodontal status of individuals with Down syndrome: sociodemographic, behavioural and family perception influence
(Journal of Intellectual Disability Research, 2019) [Artigo]Background: The aim of the present study was to assess the periodontal condition of individuals with Down syndrome and the association with sociodemographic and behavioural characteristics and family perception of oral ... -
Genes Regulating Immune Response and Amelogenesis Interact in Increasing the Susceptibility to Molar-Incisor Hypomineralization
(Caries Research, 2019) [Artigo]Ameloblasts are sensitive cells whose metabolism and function may be affected by inflammatory stimuli. The aim of this study was to evaluate the possible association between polymorphisms in immune response-related genes ... -
Functionality of the Interleukin 8 haplotypes in lymphocytes and macrophages in response to gram-negative periodontopathogens
(Gene, 2019) [Artigo]Individuals carrying the ATC/TTC haplotype (Hap-1) in the interleukin 8 (IL8) gene were reported as more susceptible to chronic periodontitis (CP), an infectious disease associated with Gram-negative bacteria, in comparison ... -
Matrix Metalloproteinase-1 and Acid Phosphatase in the Degradation of the Lamina Propria of Eruptive Pathway of Rat Molars
(Cells, 2018) [Artigo]The comprehension of dental pathogenesis and disorders derived from eruption failure requires a deep understanding of the molecular mechanisms underlying normal tooth eruption. As intense remodelling is needed during tooth ... -
Fluoxetine-induced androgenic failure impairs the seminiferous tubules integrity and increases ubiquitin carboxyl-terminal hydrolase L1 (UCHL1): Possible androgenic control of UCHL1 in germ cell death?
(Biomedicine & Pharmacotherapy, 2019) [Artigo]The selective serotonin reuptake inhibitor fluoxetine has been used for the treatment of depression. Although sexual disorders have been reported in male patients, few studies have demonstrated the fluoxetine effect on the ... -
VEGF immunoexpression related to the ectomesenchymal cells differentiation into osteoblasts during early development of alveolar process in rat molars.
(Molecular Biology Of The Cell, 2014) [Resumo] -
Estrogen improves osteocyte viability by inhibiting apoptosis and enhancing autophagy in alveolar process of ovariectomized rats.
(Molecular Biology Of The Cell, 2014) [Resumo]