Metastatic kidney carcinoma causing paralysis of pelvic limbs in a dog
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Data
2016-01-01
Autores
Calazans, S. G.
Alves, C. E.F. [UNESP]
Zanetti, N. M.
Conforti, V. A.
Santilli, J.
Anjos, D. S.
Magalhães, G. M.
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Resumo
A 12-year-old male Maltese dog was presented with a history of shivering episodes. Radiographs revealed a mass in the left kidney that was histopathologically classified as a renal cell carcinoma. After nephrectomy, pelvic limbs became paralyzed. Spinal cord and lung metastases were detected via histopathological examination and confirmed by immunohistochemistry. Both pan-cytoketatin and Ki67 assays tested positive in the kidney, lung, and spinal cord. Interestingly, COX- 2 had mild immunoreactivity in the kidney, but its labeling was intense in the spinal cord and lung. Though seemingly rare, the spinal cord may possibly be a focus point for metastasis of renal cell carcinomas. Because symptoms can easily be misunderstood, late diagnoses would not be uncommon and may hinder clinical management of the disease.
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Palavras-chave
Canine, Metastasis, Pan-cytoketatin, Renal neoplasm, Spinal cord
Como citar
Pakistan Veterinary Journal, v. 36, n. 1, p. 124-126, 2016.