Now showing items 1-10 of 31
Effects of protein-calorie restriction on mechanical function of hypertrophied cardiac muscle
(Arquivos Brasileiros de Cardiologia, 1999-04-01) [Artigo]
OBJECTIVE: To assess the effect of food restriction (FR) on hypertrophied cardiac muscle in spontaneously hypertensive rats (SHR). METHODS: Isolated papillary muscle preparations of the left ventricle (LV) of 60-day-old ...
Hypertrophied myocardium is more dependent on extracellular calcium than the normal cardiac muscle
(Case Reports and Clinical Practice Review, 2010-08-13) [Artigo]
Background: The aim of this study was to analyze stable hypertrophied myocardial function and its response to inotropic maneuvers in rats submitted to renovascular hypertension for a 10-week period (RHT group, n=10). ...
Follow-up study of morphology and cardiac function in rats undergoing induction of supravalvular aortic stenosis
(Arquivos Brasileiros de Cardiologia, 2003-12-01) [Artigo]
OBJETIVO: Caracterizar, evolutivamente, o modelo experimental de hipertrofia ventricular esquerda (HVE) por indução de estenose aórtica supravalvar em ratos jovens. MÉTODOS: Ratos Wistar foram submetidos a toracotomia para ...
Growth hormone and heart failure: Oxidative stress and energetic metabolism in rats
(Growth Hormone & Igf Research, 2008-08-01) [Artigo]
Several evidences point for beneficial effects of growth hormone (GH) in heart failure (HF). Taking into account that HF is related with changes in myocardial oxidative stress and in energy generation from metabolic pathways, ...
Differential influences of high fat diet on cardiac remodeling from normotensive and spontaneously hypertensive rats
(Circulation, 2008-09-16) [Resumo]
Exercise training increases myocardial inotropic response in food restricted rats
(International Journal of Cardiology, 2006-09-20) [Artigo]
This study evaluated the effects of exercise training on myocardial function and ultrastructure of rats submitted to different levels of food restriction (FR). Male Wistar-Kyoto rats, 60 days old, were submitted to free ...
Obesity induces upregulation of genes involved in myocardial Ca2+ handling
(Brazilian Journal of Medical and Biological Research, 2008-07-01) [Artigo]
Obesity is a complex multifactorial disorder that is often associated with cardiovascular diseases. Research on experimental models has suggested that cardiac dysfunction in obesity might be related to alterations in ...
Down-regulation of the cardiac sarcoplasmic reticulum ryanodine channel in severely food-restricted rats
(Brazilian Journal of Medical and Biological Research, 2007-01-01) [Artigo]
We have shown that myocardial dysfunction induced by food restriction is related to calcium handling. Although cardiac function is depressed in food-restricted animals, there is limited information about the molecular ...
A comparative study of myocardial function and morphology during fasting/refeeding and food restriction in rats
(Cardiovascular Pathology, 2010-09-01) [Artigo]
Background: This study compared the influence of fasting/refeeding cycles and food restriction on rat myocardial performance and morphology. Methods: Sixty-day-old male Wistar rats were submitted to food ad libitum (C), ...
Multivariate analysis for animal selection in experimental research
(Arquivos Brasileiros de Cardiologia, 2015-02-01) [Artigo]
Background: Several researchers seek methods for the selection of homogeneous groups of animals in experimental studies, a fact justified because homogeneity is an indispensable prerequisite for casualization of treatments. ...