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Echocardiographic detection of congestive heart failure in postinfarction rats
(Journal of Applied Physiology, 2011-08-01) [Artigo]
Martinez PF, Okoshi K, Zornoff LA, Oliveira Jr SA, Campos DH, Lima AR, Damatto RL, Cezar MD, Bonomo C, Guizoni DM, Padovani CR, Cicogna AC, Okoshi MP. Echocardiographic detection of congestive heart failure in postinfarction ...
Follow-up study of morphology and cardiac function in rats undergoing induction of supravalvular aortic stenosis
(Arquivos Brasileiros de Cardiologia, 2003-12-01) [Artigo]
OBJETIVO: Caracterizar, evolutivamente, o modelo experimental de hipertrofia ventricular esquerda (HVE) por indução de estenose aórtica supravalvar em ratos jovens. MÉTODOS: Ratos Wistar foram submetidos a toracotomia para ...
Chronic heart failure-induced skeletal muscle atrophy, necrosis, and changes in myogenic regulatiory factors
(Medical Science Monitor, 2010-12-01) [Artigo]
Background: Although intrinsic skeletal muscle abnormalities can influence exercise intolerance during heart failure (HF), the factors responsible for muscle changes have not been elucidated. In this study we evaluated the ...
Obesity induces upregulation of genes involved in myocardial Ca2+ handling
(Brazilian Journal of Medical and Biological Research, 2008-07-01) [Artigo]
Obesity is a complex multifactorial disorder that is often associated with cardiovascular diseases. Research on experimental models has suggested that cardiac dysfunction in obesity might be related to alterations in ...
Food restriction impairs myocardial inotropic response to calcium and beta-adrenergic stimulation in spontaneously hypertensive rats
(Nutrition Research, 2008-10-01) [Artigo]
Although long-term food restriction (FR) has been shown to induce cardiac remodeling and dysfunction, there arc few data on the effects of FR on pressure-overloaded hearts. The aim of this study was to examine the effects ...
Pharmacological dose of alpha-tocopherol induces cardiotoxicity in Wistar rats determined by echocardiography and histology
(Human & Experimental Toxicology, 2011-10-01) [Artigo]
The effect of pharmacological dose of cc-tocopherol on heart health was determined in Wistar rats. Animals were randomly assigned to either C (control, n = II) or E (cc-tocopherol, n = II) group. Animals received corn oil ...
Obesity Preserves Myocardial Function During Blockade of the Glycolytic Pathway
(Arquivos Brasileiros de Cardiologia, 2014-10-01) [Artigo]
Background: Obesity is defined by excessive accumulation of body fat relative to lean tissue. Studies during the last few years indicate that cardiac function in obese animals may be preserved, increased or diminished. ...
Aerobic training attenuates nicotinic acetylcholine receptor changes in the diaphragm muscle during heart failure
(Histology and Histopathology, 2015-01-01) [Artigo]
Introduction: Heart failure (HF) is a progressive myopathy, with clinical signs of fatigue and limb weakness that can damage the nerve-muscle interaction, altering synaptic transmission and nicotinic acetylcholine receptors ...
Severe food restriction induces myocardial dysfunction related to SERCA2 activity
(Canadian Journal of Physiology and Pharmacology, 2009-09-01) [Artigo]
Previous studies have shown that food restriction promotes myocardial dysfunction in rats. However, the molecular mechanisms that are responsible are unclear. We investigated the role of sarcoplasmic reticulum Ca(2+)-ATPase ...