Now showing items 1-5 of 5
Differential morphofunctional characteristics and gene expression in fast and slow muscle of rats with monocrotaline-induced heart failure
(Journal of Molecular Histology, 2011-06-01) [Artigo]
Heart failure (HF) is characterized by limited exercise tolerance, skeletal muscle atrophy, a shift toward fast muscle fiber, and myogenic regulatory factor (MRF) changes. Reactive oxygen species (ROS) also contribute to ...
Multivariate analysis for animal selection in experimental research
(Arquivos Brasileiros de Cardiologia, 2015-02-01) [Artigo]
Background: Several researchers seek methods for the selection of homogeneous groups of animals in experimental studies, a fact justified because homogeneity is an indispensable prerequisite for casualization of treatments. ...
Administration of physiologic levels of triiodothyronine increases leptin expression in calorie-restricted obese rats, but does not influence weight loss
(Metabolism-clinical and Experimental, 2010-01-01) [Artigo]
Obesity has become a major public health problem, most commonly treated via dietary restriction to promote weight loss. Although leptin and thyroid hormones are involved in the regulation of energy balance, the role of ...
Pharmacological dose of alpha-tocopherol induces cardiotoxicity in Wistar rats determined by echocardiography and histology
(Human & Experimental Toxicology, 2011-10-01) [Artigo]
The effect of pharmacological dose of cc-tocopherol on heart health was determined in Wistar rats. Animals were randomly assigned to either C (control, n = II) or E (cc-tocopherol, n = II) group. Animals received corn oil ...
Obesity Preserves Myocardial Function During Blockade of the Glycolytic Pathway
(Arquivos Brasileiros de Cardiologia, 2014-10-01) [Artigo]
Background: Obesity is defined by excessive accumulation of body fat relative to lean tissue. Studies during the last few years indicate that cardiac function in obese animals may be preserved, increased or diminished. ...