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dc.contributor.authorJorge Neto, Salim Demétrio
dc.contributor.authorMachado, Jackeline Souza Rangel
dc.contributor.authorPalei, Ana Carolina Tavares
dc.contributor.authorMartins, Wellington Paula
dc.contributor.authorSandrim, Valéria Cristina [UNESP]
dc.contributor.authorAraujo Júnior, Edward
dc.contributor.authorAmaral, Lorena Machado
dc.contributor.authorTanus-Santos, José Eduardo
dc.contributor.authorDuarte, Geraldo
dc.contributor.authorCavalli, Ricardo Carvalho
dc.identifier.citationJournal of Maternal-Fetal and Neonatal Medicine, v. 29, n. 20, p. 3406-3409, 2016.
dc.description.abstractObjective: The objective was to evaluate and compare the whole blood nitrite concentration in the three trimesters of pregnancy. Additionally, we investigate whether there is any relation between nitrite concentrations and Doppler ultrasound analysis of some maternal and fetal vessels. Methods: Thirty-three healthy pregnant women were examined at the first (11–14 weeks), second (20–24 weeks) and third trimester (34–36 weeks) of pregnancy. In the three exams, we determined the maternal whole blood nitrite concentration and uterine arteries Doppler analysis to determine pulsatility index (PI), and resistance index (RI). In the second and third trimester we also performed fetal umbilical and middle cerebral arteries PI and RI. We compared the concentrations of nitrite in three trimesters and correlated with Doppler parameters. Results: No difference was observed in the whole blood nitrite concentrations across trimesters: 151.70 ± 77.90 nmol/ml, 142.10 ± 73.50 nmol/ml and 147.10 ± 87.30 nmol/ml; first, second and third trimesters, respectively. We found no difference in correlation between whole blood nitrite concentration and Doppler parameters from the evaluated vessels. Conclusions: In healthy pregnant women, the nitrite concentrations did not change across gestational trimesters and there was also no strong correlation with Doppler impedance indices from maternal uterine arteries and fetal umbilical and middle cerebral arteries.en
dc.relation.ispartofJournal of Maternal-Fetal and Neonatal Medicine
dc.subjectDoppler ultrasonography
dc.titleAssessment of nitrite oxide and maternal–fetal Doppler parameters during pregnancyen
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversity of Mississipi Medical Center
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.description.affiliationDepartment of Obstetrics and Gynecology Ribeirao Preto Medical School University of Sao Paulo (FMRP-USP)
dc.description.affiliationDepartament of Physiology and Biophysics University of Mississipi Medical Center
dc.description.affiliationDepartament of Pharmacology Botucatu Medical School São Paulo State University (UNESP)
dc.description.affiliationDepartment of Obstetrics Paulista School of Medicine Federal University of São Paulo (EPM-UNIFESP)
dc.description.affiliationDepartament of Pharmacology Ribeirão Preto Medical School University of Sao Paulo (FMRP-USP)
dc.description.affiliationUnespDepartament of Pharmacology Botucatu Medical School São Paulo State University (UNESP)
dc.rights.accessRightsAcesso aberto
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