Recent Submissions

  • Can the antral follicular count modulate the gene expression of bovine oviducts in Aberdeen angus and nelore heifers?

    Fontes, Patricia Kubo Autor UNESP; Ereno, Ronaldo Luis Autor UNESP; Peixoto, André Rebello Autor UNESP; Carvalho, Robson Francisco Autor UNESP; Scarano, Wellerson Rodrigo Autor UNESP; Trinca, Luzia Aparecida Autor UNESP; Barros, Ciro Moraes Autor UNESP; de Souza Castilho, Anthony César (PLoS ONE, 2018) [Artigo]
    The number of visible ovarian antral follicles (antral follicle count—AFC) is repeatable in bovine individuals, but highly variable between animals, and with differences between Bos taurus and Bos indicus breeds. Several ...
  • Pharmacological characterization of cnidarian extracts from the Caribbean Sea: Evaluation of anti-snake venom and antitumor properties

    Oliveira, Cláudia S.; Caldeira, Cleópatra A.S.; Diniz-Sousa, Rafaela; Romero, Dolores L.; Marcussi, Silvana; Moura, Laura A.; Fuly, André L.; de Carvalho, Cicília Autor UNESP; Cavalcante, Walter L.G. Autor UNESP; Gallacci, Márcia Autor UNESP et al. (Journal of Venomous Animals and Toxins Including Tropical Diseases, 2018) [Artigo]
    Background: Cnidarians produce toxins, which are composed of different polypeptides that induce pharmacological effects of biotechnological interest, such as antitumor, antiophidic and anti-clotting activities. This study ...
  • Structural basis of phospholipase A2-like myotoxin inhibition by chicoric acid, a novel potent inhibitor of ophidian toxins

    Cardoso, Fábio F. Autor UNESP; Borges, Rafael J. Autor UNESP; Dreyer, Thiago R. Autor UNESP; Salvador, Guilherme H.M. Autor UNESP; Cavalcante, Walter L.G. Autor UNESP; Pai, Maeli Dal Autor UNESP; Gallacci, Márcia Autor UNESP; Fontes, Marcos R.M. Autor UNESP (Biochimica et Biophysica Acta - General Subjects, 2018) [Artigo]
    Background: Specific compounds found in vegetal species have been demonstrated to be efficient inhibitors of snake toxins, such as phospholipase A2-like (PLA2-like) proteins. These particular proteins, present in several ...
  • Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism

    Salvador, Guilherme H. M. Autor UNESP; Dreyer, Thiago R. Autor UNESP; Gomes, Antoniel A. S. Autor UNESP; Cavalcante, Walter L. G. Autor UNESP; Dos Santos, Juliana I. Autor UNESP; Gandin, César A. Autor UNESP; De Oliveira Neto, Mário Autor UNESP; Gallacci, Márcia Autor UNESP; Fontes, Marcos R. M. Autor UNESP (Scientific Reports, 2018) [Artigo]
    Local myonecrosis is the main event resulting from snakebite envenomation by the Bothrops genus and, frequently, it is not efficiently neutralized by antivenom administration. Proteases, phospholipases A2 (PLA2) and PLA2-like ...
  • The Effect of Schinus terebinthifolius Raddi (Anacardiaceae) Bark Extract on Histamine-Induced Paw Edema and Ileum Smooth Muscle Contraction

    Nunes-Neto, Paulo Alexandre; Peixoto-Sobrinho, Tadeu José Da Silva; Da Silva Júnior, Edilson Dantas; Leopoldina Da Silva, Jamilka; Rodrigo Da Silva Oliveira, Alisson; Pupo, André Sampaio Autor UNESP; Araújo, Alice Valencą; Costa-Silva, Joaõ Henrique Da; Wanderley, Almir Goncąlves (Evidence-based Complementary and Alternative Medicine, 2017) [Artigo]
    Schinus terebinthifolius Raddi (Anacardiaceae), popularly known as red aroeira, is used in traditional medicine to treat inflammatory, gastric, and respiratory disorders. The aim of this study was to evaluate the antihistaminic ...
  • C>T (rs17035945) polymorphism of TIMP-4 protects against preeclampsia

    Sandrim, Valéria C.; Luizon, Marcelo R.; Machado, Jackeline S. R.; Cavalli, Ricardo C. (Journal of Obstetrics and Gynaecology, 2018) [Artigo]
  • Circulating microRNA expression profiles in pre-eclampsia: evidence of increased miR-885-5p levels

    Sandrim, V. C.; Luizon, M. R.; Palei, A. C.; Tanus-Santos, J. E.; Cavalli, R. C. (BJOG : an international journal of obstetrics and gynaecology, 2016) [Artigo]
    OBJECTIVE: To validate and to compare the circulating microRNA (miR) expression profiles between pre-eclampsia and healthy pregnant women, to perform correlation analysis of the differently expressed miRs with clinical and ...
  • Tobacco influence in heavy metals levels in head and neck cancer cases

    Bandeira, Celso Muller Autor UNESP; de Almeida, Adriana Ávila Autor UNESP; Carta, Celina Faig Lima; Almeida, Alaor Aparecido Autor UNESP; de Figueiredo, Fellipe Augusto Tocchini Autor UNESP; Sandrim, Valeria Cristina Autor UNESP; Gonçalves, Antonio José; Almeida, Janete Dias Autor UNESP (Environmental Science and Pollution Research, 2018) [Artigo]
    Heavy metals intoxication is known to be risk factors for various diseases, including cancer. These metals may be presented in food and soil as well as in leaf and tobacco smoke. The aim of this study was to correlate the ...
  • Author Correction: Myeloperoxidase is not a good biomarker for preeclampsia prediction

    Rocha-Penha, L. Autor UNESP; Bettiol, H.; Barbieri, M. A.; Cardoso, V. C.; Cavalli, R. C.; Sandrim, V. C. Autor UNESP (Scientific Reports, 2018) [Errata]
    Te authors acknowledge the Conselho Nacional de Desenvolvimento Científco e Tecnológico (CNPq-Brazil), the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES-Brazil), and the Fundação de Amparo à Pesquisa ...
  • Prevalence of metabolic syndrome and framingham risk score in apparently healthy vegetarian and omnivorous men

    Navarro, Julio Cesar Acosta; Antoniazzi, Luiza; Oki, Adriana Midori; Bonfim, Maria Carlos; Hong, Valeria; Bortolotto, Luiz Aparecido; Acosta-Cardenas, Pedro; Sandrim, Valeria Autor UNESP; Miname, Marcio Hiroshi; Dos Santos Filho, Raul Dias (Arquivos Brasileiros de Cardiologia, 2018) [Artigo]
    Background: Recent studies have shown a lower prevalence of metabolic syndrome (MSyn) in vegetarians (VEG) despite the inconclusive evidence from others. Objective: To verify the association between diet and other lifestyle ...
  • Corrigendum to “Neuromuscular synapse degeneration without muscle function loss in the diaphragm of a murine model for Huntington's Disease"

    Valadão, Priscila A.C.; Gomes, Matheus P.S.M.; Aragão, Bárbara C.; Rodrigues, Hermann A.; Andrade, Jéssica N.; Garcias, Rubens; Joviano-Santos, Julliane V.; Luiz, Murilo A.; Camargo, Wallace L.; Naves, Lígia A. et al. (Neurochemistry International, 2018) [Errata]
    The authors regret that the trace in Fig. 6H was the same as from Fig. 6I. We have inserted the correct trace in Fig. 6H. The authors would like to apologise for any inconvenience caused.
  • Levels of MMP-9 in patients with intracranial aneurysm: Relation with risk factors, size and clinical presentation

    Rojas, Hugo Alberto; Fernandes, Karla Simone da Silva; Ottone, Mariana Rodrigues; Magalhães, Kênia Cristina S. Fonseca de; Albuquerque, Lucas Alverne Freitas de; Pereira, Julio Leonardo Barbosa; Vieira-Júnior, Gerival; Sousa-Filho, José Lopes; Costa, Bruno Silva; Sandrim, Valéria Cristina Autor UNESP et al. (Clinical Biochemistry, 2018) [Artigo]
    Background: Intracranial aneurysms are arterial anomalies affecting 2% to 3% of the general population in the world and these ruptures are associated with a high mortality. Some risk factors, such as age, gender, smoking, ...
  • Neuromuscular synapse degeneration without muscle function loss in the diaphragm of a murine model for Huntington's Disease

    Valadão, Priscila A.C.; Gomes, Matheus P.S.M.; Aragão, Bárbara C.; Rodrigues, Hermann A.; Andrade, Jéssica N.; Garcias, Rubens; Joviano-Santos, Julliane V.; Luiz, Murilo A.; Camargo, Wallace L.; Naves, Lígia A. et al. (Neurochemistry International, 2018) [Artigo]
    Huntington's disease (HD) is an autosomal dominant neurodegenerative disease characterized by chorea, incoordination and psychiatric and behavioral symptoms. The leading cause of death in HD patients is aspiration pneumonia, ...
  • Chemical composition and bioactivity of essential oil from blepharocalyx salicifolius

    Furtado, Fabiana Barcelos Autor UNESP; Borges, Bruna Cristina; Teixeira, Thaise Lara; Garces, Hans Garcia Autor UNESP; De Almeida Junior, Luiz Domingues Autor UNESP; Alves, Fernanda Cristina Bérgamo Autor UNESP; Da Silva, Claudio Vieira; Fernandes Junior, Ary Autor UNESP (International Journal of Molecular Sciences, 2018) [Artigo]
    Natural products represent a source of biologically active molecules that have an important role in drug discovery. The aromatic plant Blepharocalyx salicifolius has a diverse chemical constitution but the biological ...
  • Oxidative Stress Alters the Profile of Transcription Factors Related to Early Development on in Vitro Produced Embryos

    Leite, Roberta Ferreira; Annes, Kelly; Ispada, Jessica; De Lima, Camila Bruna; Dos Santos, Érika Cristina; Fontes, Patricia Kubo Autor UNESP; Nogueira, Marcelo Fábio Gouveia Autor UNESP; Milazzotto, Marcella Pecora (Oxidative Medicine and Cellular Longevity, 2017) [Artigo]
    High oxygen levels during in vitro culture (IVC) can induce oxidative stress through accumulation of reactive oxygen species (ROS), negatively affecting embryo development. This study evaluated the effect of different O 2 ...
  • Effect of superstimulation on the expression of microRNAs and genes involved in steroidogenesis and ovulation in Nelore cows

    Santos, P. H. Autor UNESP; Satrapa, R. A.; Fontes, P. K. Autor UNESP; Franchi, F. F. Autor UNESP; Razza, E. M. Autor UNESP; Mani, F. Autor UNESP; Nogueira, M. F.G. Autor UNESP; Barros, C. M. Autor UNESP; Castilho, A. C.S. Autor UNESP (Theriogenology, 2018) [Artigo]
    To better understand the impact of ovarian superstimulation on bovine follicular microenvironment, Nelore cows (Bos taurus indicus) were subjected to ovarian superstimulation with follicle stimulating hormone (FSH, n = 10; ...
  • Maternal hypertension and feto-placental growth restriction is reversed by sildenafil: Evidence of independent effects of circulating nitric oxide levels

    Gonçalves-Rizzi, Victor Hugo Autor UNESP; Possomato-Vieira, José Sérgio Autor UNESP; Nascimento, Regina Aparecida Autor UNESP; Caldeira-Dias, Mayara Autor UNESP; Dias-Junior, Carlos Alan Autor UNESP (European Journal of Pharmacology, 2018) [Artigo]
    Sildenafil has shown nitric oxide (NO)-independent pleiotropic effects, however the mechanisms involved are unclear. We investigated the protective effects of sildenafil against hypertension in pregnancy and feto-placental ...
  • The role of cGMP as a mediator of lipolysis in bovine oocytes and its effects on embryo development and cryopreservation

    Schwarz, Kátia R. L.; de Castro, Fernanda C; Schefer, Letícia; Botigelli, Ramon C. Autor UNESP; Paschoal, Daniela M.; Fernandes, Hugo; Leal, Cláudia L. V. (PLoS ONE, 2018) [Artigo]
    This study aimed to determine the influence of cyclic guanosine 3’5’-monophosphate (cGMP) and cGMP-dependent kinase (PKG) during in vitro maturation (IVM) on lipolysis-related parameters in bovine cumulus-oocyte complexes ...
  • Genome-wide screening of DNA methylation in bovine blastocysts with different kinetics of development

    Ispada, Jessica; De Lima, Camila Bruna; Sirard, Marc-André; Fontes, Patrícia Kubo Autor UNESP; Nogueira, Marcelo Fábio Gouveia Autor UNESP; Annes, Kelly; Milazzotto, Marcella Pecora (Epigenetics and Chromatin, 2018) [Artigo]
    Background: The timing of the first cell divisions may predict the developmental potential of an embryo, including its ability to establish pregnancy. Besides differences related to metabolism, stress, and survival, embryos ...
  • Cardiac myeloperoxidase activity is elevated in hypertensive pregnant rats

    Zhu, Ming-lin; Zhao, Jin-ping; Cui, Ning; Gonçalves-Rizzi, Victor H. Autor UNESP; Possomato-Vieira, Jose S. Autor UNESP; Nascimento, Regina A. Autor UNESP; Dias-Junior, Carlos A. Autor UNESP (Journal of Huazhong University of Science and Technology - Medical Science, 2017) [Artigo]
    Myeloperoxidase (MPO) is released from activated neutrophils. The inflammation in preeclampsia was found to be associated with endothelial dysfunction. We hypothesized that cardiac and circulating MPO levels are elevated ...

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