Hypoxia effects on oxidative stress and immunocompetence biomarkers in the mussel Perna perna (Mytilidae, Bivalvia)
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Data
2017-01-01
Autores
Nogueira, L�lian [UNESP]
Mello, Danielle Ferraz
Trevisan, Rafael
Garcia, Danielly [UNESP]
da Silva Acosta, Daiane
Dafre, Alcir Luiz
de Almeida, Eduardo Alves [UNESP]
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Resumo
This study investigated the effects of hypoxia on oxidative stress response and immune function in mussels Perna perna exposed to air for 6, 12, 24 and 48�h. In air-exposed mussels, the antioxidant enzymes superoxide dismutase (SOD), catalase, and glutathione reductase (GR) activities were lower in gill tissues (24–48�h) and digestive gland (12�h), while the glutathione peroxidase and GR activities were increased in the digestive gland (48�h). In both tissues, aerial exposure promoted a rapid (6�h) and persistent (up to 48�h) increase of glutathione levels. Decreased hemocyte count and viability, as well as increased phagocytic activity and cellular adhesion capacity were detected after prolonged aerial exposure (>12�h). In summary, induction of thiol pools, altered antioxidant enzyme activities, and activation of immune responses were detected in hypoxia exposed brown mussels, indicating hypoxia induced tissue-specific responses in both antioxidant and immune systems.
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Antioxidant defenses, Bivalves, Hemocytes, Immune system, Reduced oxygen levels
Como citar
Marine Environmental Research, v. 126, p. 109-115.