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dc.contributor.authorMendaçolli, Paola Jung [UNESP]
dc.contributor.authorSchmitt, Juliano Vilaverde [UNESP]
dc.contributor.authorMiot, Hélio Amante [UNESP]
dc.contributor.authorBrianezi, Gabrielli [UNESP]
dc.contributor.authorMarques, Mariângela Esther Alencar [UNESP]
dc.date.accessioned2018-12-11T17:26:43Z
dc.date.available2018-12-11T17:26:43Z
dc.date.issued2015-11-01
dc.identifierhttp://dx.doi.org/10.1590/abd1806-4841.20154076
dc.identifier.citationAnais Brasileiros de Dermatologia, v. 90, n. 6, p. 874-878, 2015.
dc.identifier.issn1806-4841
dc.identifier.issn0365-0596
dc.identifier.urihttp://hdl.handle.net/11449/177707
dc.description.abstractHistological subtypes of basal cell carcinoma have biological, evolutionary and distinct prognostic behavior. The analysis of characteristics of the nucleus can provide data on their cellular physiology and behavior. The authors of this study evaluated nuclear morphological parameters and textural patterns of chromatin from different subtypes of basal cell carcinoma: nodular (n=37), superficial (n=28) and sclerodermiform (n=28). The parameters were compared between neoplasms’ subtypes and with unaffected adjacent basal epithelium. Nuclear area and diameter of sclerodermiform neoplasms were superior to the other subtypes. Chromatin’s color intensity and fractal dimension were less intense in superficial subtypes. Nuclear roundness and chromatin’s entropy presented lower values in tumors than in normal epithelium. There was significant correlation between morphological and textural variables of normal skin and tumors. Morphometric elements and textural chromatin’s homogeneity of basal cell carcinomas may be related to evolutionary, biological and behavior particularities related to each histotype.en
dc.format.extent874-878
dc.language.isoeng
dc.relation.ispartofAnais Brasileiros de Dermatologia
dc.sourceScopus
dc.subjectBasal cell
dc.subjectCarcinoma
dc.subjectChromatin
dc.subjectComputer-assisted
dc.subjectImage processing
dc.subjectKaryometry
dc.subjectPrognosis
dc.titleNuclear morphometry and chromatin textural characteristics of basal cell carcinomaen
dc.typeArtigo
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationUniversidade Estadual Paulista ‘Júlio de Mesquita Filho’ (Unesp)
dc.description.affiliationUnespUniversidade Estadual Paulista ‘Júlio de Mesquita Filho’ (Unesp)
dc.identifier.doi10.1590/abd1806-4841.20154076
dc.identifier.scieloS0365-05962015000600874
dc.rights.accessRightsAcesso aberto
dc.identifier.scopus2-s2.0-84953874691
dc.identifier.fileS0365-05962015000600874.pdf
dc.relation.ispartofsjr0,520
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