Syndrome in question: Antisynthetase syndrome (anti-PL-7)
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Data
2016-09-01
Autores
Esposito, Ana Cláudia Cavalcante [UNESP]
Miot, Hélio Amante [UNESP]
Gige, Tatiana Cristina [UNESP]
Título da Revista
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Resumo
Antisynthetase syndrome is a rare autoimmune disease characterized by interstitial lung disease and/or inflammatory myositis, with positive antisynthetase antibodies (anti-Jo-1, anti-PL-7, anti-PL-12, ZO, OJ, anti-KE or KS). Other symptoms described include: non-erosive arthritis, fever, Raynaud’s phenomenon, and mechanic’s hands. The first therapeutic option is corticotherapy, followed by other immunosuppressants. The prognosis of the disease is quite limited when compared to other inflammatory myopathies with negative antisynthetase antibodies.
Descrição
Palavras-chave
Amino Acyl-tRNA synthetases, Interstitial lung disease, Myositis
Como citar
Anais Brasileiros de Dermatologia, v. 91, n. 5, p. 679-681, 2016.