RSS 1.0Artigos - Genética - IBB
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The Long Non-Coding RNA SNHG12 as a Mediator of Carboplatin Resistance in Ovarian Cancer via Epigenetic Mechanisms
; ; Rainho, Cláudia Aparecida
; ; Calanca, Naiade ; ; ; (Cancers, 2022) [Artigo]
Genetic and epigenetic changes contribute to intratumor heterogeneity and chemotherapy resistance in several tumor types. LncRNAs have been implicated, directly or indirectly, in the epigenetic regulation of gene expression. ... -
Comprehensive In Silico Analysis and Transcriptional Profiles Highlight the Importance of Mitochondrial Dicarboxylate Carriers (DICs) on Hypoxia Response in Both Arabidopsis thaliana and Eucalyptus grandis
Barreto, Pedro; Arcuri, Mariana L. C. ; Lima, Rômulo Pedro Macêdo ; Marino, Celso Luis ; Maia, Ivan G. (Plants, 2022) [Artigo]
Plant dicarboxylate carriers (DICs) transport a wide range of dicarboxylates across the mitochondrial inner membrane. The Arabidopsis thaliana DIC family is composed of three genes (AtDIC1, 2 and 3), whereas two genes ... -
Brazilian green propolis: A novel tool to improve the cytotoxic and immunomodulatory action of docetaxel on MCF-7 breast cancer cells and on women monocyte
de Oliveira Cardoso, Eliza; Santiago, Karina Basso ; Conti, Bruno José ; Conte, Fernanda Lopes ; Tasca, Karen Ingrid ; ; de Assis Golim, Marjorie ; Rainho, Cláudia Aparecida ; ; Sforcin, José Maurício (Phytotherapy Research, 2022) [Artigo]
Docetaxel (DTX) is used against breast cancer despite its side effects such as toxicity and immunosuppression. Here we investigated the cytotoxic and immunomodulatory effects of the ethanol solution extract of propolis ... -
Systemic treatment of penile squamous cell carcinoma—hurdles and hopes of preclinical models and clinical regimens: a narrative review
; ; Rainho, Claudia Aparecida; ; ; ; ; (Translational Andrology and Urology, 2021) [Resenha]
Despite contemporary research efforts, the prognosis of penile squamous cell carcinoma (PeSCC) has not significantly improved over the past decade. Despite frequently encountered patient-related delayed medical consultations ... -
Physical, functional and biochemical features of Nanoskin® bacterial cellulose scaffold as a potential carrier for cell transference
Viveiros, Magda Massae Hata; Rainho, Cláudia Aparecida ; Ramirez, Jofer Andree Zamame ; Kaneno, Ramon ; Silva, Márcia Guimarães ; Ximenes, Valdecir Farias ; ; ; ; Schellini, Silvana Artioli (Materials Letters, 2022) [Artigo]
We evaluated the feasibility of Nanoskin®, a bacterial cellulose (BC) nanofiber membrane, as a potential scaffold for cell transference therapy. Nanoskin® does not induce lymphocyte proliferation, but it does not kill ... -
DNA barcode regions for differentiating Cattleya walkeriana and C. loddigesii
Rivera-Jiménez, Hernando; Rossini, Bruno César ; Tambarussi, Evandro Vagner ; ; ; Marino, Celso Luis (Acta Scientiarum - Biological Sciences, 2017) [Artigo]
Growers appreciate Cattleya walkeriana and C. loddigesii due to striking shape and rarity. Thus, this study aimed to evaluate the feasibility of DNA barcode regions, namely ITS1, ITS2 and rpoC1, to discriminate between C. ... -
Persistência e liberação de macronutrientes e silício da fitomassa de crotalária em função da fragmentação
da Costa, Claudio Hideo Martins; Crusciol, Carlos Alexandre Costa ; Soratto, Rogério Peres ; Ferrari Neto, Jayme (Bioscience Journal, 2012) [Artigo]
The persistence of straw, as well as the dynamics of nutrients release of it, are important aspects to consider in the choice of plants for composition of crop rotations in a no tillage system. Thus, the objective of this ... -
Studies of the human sex ratio and factors influencing family size in Botucatu, Brazil
; Bortolozzi, Jehud (Journal of Heredity, 1977) [Artigo]
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Yeast Double Transporter Gene Deletion Library for Identification of Xenobiotic Carriers in Low or High Throughput
; ; ; ; ; ; ; ; Klippel, Angélica Hollunder; Silva, Suélen Fernandes et al. (mBio, 2021) [Artigo]
The routes of uptake and efflux should be considered when developing new drugs so that they can effectively address their intracellular targets. As a general rule, drugs appear to enter cells via protein carriers that ... -
Estudo citogenético em eqüinos para detecção de portadores de monossomia do cromossomo X
(Arquivo Brasileiro de Medicina Veterinaria e Zootecnia, 1996) [Artigo]A cytogenetic study of 22 mares with fertility has showed that four of them had 63,X/64,XX mosaicism. The X-chromosome has presented the expected interstitial heterochromatic C - banding located in the long arm, besides ... -
A complex chromosomal rearrangement detected prenatally and studied by fluorescence in situ hybridization
(Human Genetics, 1993) [Artigo]We report of case of a complex chromosomal rearrangement detected prenatally and studied with traditional banding methods and fluorescence in situ hybridization. The combination of these techniques showed that four chromosomes ... -
Phylogenetic studies of some species of the genus Coffea. I. Numerical analysis of flavonoid compounds
(Revista Brasileira de Genetica, 1991) [Artigo] -
Populational study of chromosome polymorphism in Zonotrichia capensis (Emberizidae, Passeriformes, Aves)
(Revista Brasileira de Genetica, 1991) [Artigo] -
Chromosome studies in males affected by Duchenne or Becker muscular dystrophy
(Revista Brasileira de Genetica, 1990) [Artigo] -
Karyotype studies in twenty-two species of parrots (Psittaciformes:Aves)
(Revista Brasileira de Genetica, 1991) [Artigo] -
Chromosome study on the maned sloth Bradypus torquatus (Bradypodidae, Xenarthra)
(Cytobios, 1990) [Artigo] -
Genetics of acheiropodia (the handless and footless families of Brazil). VI. Formal genetic analysis
(American Journal of Human Genetics, 1975) [Artigo]A genetic analysis is presented of data from 22 Brazilian sibships with cases of acheiropodia (the handless and footless families of Brazil). Segregation analysis performed using a 16K CDC 3100 computer showed a segregation ... -
Genetics of acheiropodia (the handless and footless families of Brazil). VII. Population dynamics
(American Journal of Human Genetics, 1975) [Artigo]Since carriers of the acheiropodia gene cannot be distinguished from noncarriers, parents and normal sibs of affected individuals have been used to estimate the fitness of heterozygotes. No significant difference in biologic ... -
Human genetic studies in areas of high natural radiation. VIII. Genetic load not related to radiation
(American Journal of Human Genetics, 1975) [Artigo]The genetic load disclosed by inbreeding has been analyzed in a multiple regression model for a population involving several localities in the state of Espirito Santo, Brazil. The inbreeding load has been estimated for the ... -
Genetics of acheiropodia ('the handless and footless families of Brazil'). IX. Genetic counseling
(Human Heredity, 1975) [Artigo]Acheiropodia offers no special problem of a counseling nature. The genetic risk can be easily estimated since the anomaly is due to a rare autosomal recessive gene with complete penetrance and little variation in expression. ...