Show simple item record

dc.contributor.authorLima, Celina Faig
dc.contributor.authorAcay, Renata [UNESP]
dc.contributor.authorAnbinder, Ana Lia [UNESP]
dc.contributor.authorAlmeida, Janete Dias [UNESP]
dc.contributor.authorCarvalho, Yasmin Rodarte [UNESP]
dc.date.accessioned2018-12-11T17:30:35Z
dc.date.available2018-12-11T17:30:35Z
dc.date.issued2016-11-01
dc.identifierhttp://dx.doi.org/10.1590/0103-6440201600957
dc.identifier.citationBrazilian Dental Journal, v. 27, n. 6, p. 781-786, 2016.
dc.identifier.issn1806-4760
dc.identifier.issn0103-6440
dc.identifier.urihttp://hdl.handle.net/11449/178482
dc.description.abstractAdenosquamous carcinoma is an aggressive variant of squamous cell carcinoma. This report describes a case of adenosquamous carcinoma with clinical features of a benign lesion and discusses the differential diagnoses, especially regarding histopathological and immunohistochemical analyses. A 45-year-old male was referred to our outpatient clinic complaining about a rapid-growing enlargement in hard palate. Clinical examination revealed an erythematous and pedunculated nodule with lobulated non-ulcerated surface. Excisional biopsy was performed following clinical diagnosis of pyogenic granuloma. Histologically, the specimen consisted of areas characterizing both welldifferentiated squamous cell carcinoma and true adenocarcinoma. After a broad list of immunohistochemical markers was evaluated (AE1/AE3, CEA, CK5, CK7, CK8/18, p53, p63 and Ki67), the diagnosis of adenosquamous carcinoma was rendered and the patient referred to complementary surgery. Adenosquamous carcinoma represents a challenge in diagnostic routine due to its rarity, diverse range of clinical presentations and histological features. Furthermore, classical clinical benign features may be present in malignant lesions; hence the submission of every surgical specimen to histological analysis is mandatory to provide the patient the adequate treatment.en
dc.format.extent781-786
dc.language.isoeng
dc.relation.ispartofBrazilian Dental Journal
dc.sourceScopus
dc.subjectAdenosquamous carcinoma
dc.subjectImmunohistochemistry
dc.subjectMouth mucosa
dc.subjectSquamous cell carcinoma
dc.titleOral adenosquamous carcinoma mimicking a pyogenic granuloma: A challenging diagnosisen
dc.typeArtigo
dc.contributor.institutionMogi das Cruzes
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationUniversity Braz Cubas Mogi das Cruzes
dc.description.affiliationDepartment of Bioscience and Oral Diagnosis S�o Paulo State University (UNESP) Institute of Science and Technology
dc.description.affiliationUnespDepartment of Bioscience and Oral Diagnosis S�o Paulo State University (UNESP) Institute of Science and Technology
dc.identifier.doi10.1590/0103-6440201600957
dc.identifier.scieloS0103-64402016000600781
dc.rights.accessRightsAcesso aberto
dc.identifier.scopus2-s2.0-85006124254
dc.identifier.fileS0103-64402016000600781.pdf
unesp.author.lattes6097967943008273[3]
unesp.author.orcid0000-0003-3930-4274[3]
dc.relation.ispartofsjr0,476
Localize o texto completo

Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record