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dc.contributor.authorFontes, Patricia Kubo [UNESP]
dc.contributor.authorEreno, Ronaldo Luis [UNESP]
dc.contributor.authorPeixoto, André Rebello [UNESP]
dc.contributor.authorCarvalho, Robson Francisco [UNESP]
dc.contributor.authorScarano, Wellerson Rodrigo [UNESP]
dc.contributor.authorTrinca, Luzia Aparecida [UNESP]
dc.contributor.authorBarros, Ciro Moraes [UNESP]
dc.contributor.authorde Souza Castilho, Anthony César
dc.date.accessioned2018-12-11T17:38:23Z
dc.date.available2018-12-11T17:38:23Z
dc.date.issued2018-08-01
dc.identifierhttp://dx.doi.org/10.1371/journal.pone.0202017
dc.identifier.citationPLoS ONE, v. 13, n. 8, 2018.
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/11449/180153
dc.description.abstractThe number of visible ovarian antral follicles (antral follicle count—AFC) is repeatable in bovine individuals, but highly variable between animals, and with differences between Bos taurus and Bos indicus breeds. Several studies have tried to determine the correlation between AFC and increased fertility in cattle. While the impacts of AFC on embryo production, hormonal levels, and pregnancy rates have been described, the molecular effects of AFC on bovine oviducts have not yet been investigated. Here, the aim was to investigate the impact of breeds, such as Aberdeen Angus and Nelore heifer with high or low AFC, on abundance of transcripts and protein related to oviductal transport, sperm reservoir formation, monospermy control, and gamete interaction in the oviducts. In summary, the ovulation side was the major factor that affected transcript abundance on bovine oviducts. However, a discreet effect among AFC and cattle breeds was also observed. Based on this, we concluded and reinforced here that differential microenvironments between ipsilateral and contralateral oviducts have a major effect on modulating the transcripts related to oviductal transport, sperm reservoir formation, monospermy control, and gamete interaction. However, we cannot exclude that there is minimal effect of AFC or breed on regulation of some genes (such as AGTR1, ACE1, FUCA1, and VEGFA) in bovine oviducts.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.language.isoeng
dc.relation.ispartofPLoS ONE
dc.sourceScopus
dc.titleCan the antral follicular count modulate the gene expression of bovine oviducts in Aberdeen angus and nelore heifers?en
dc.typeArtigo
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversity of Western São Paulo (UNOESTE)
dc.description.affiliationDepartament of Pharmacology Institute of Biosciences Universidade Estadual Paulista (UNESP)
dc.description.affiliationDepartament of Morphology Institute of Biosciences Universidade Estadual Paulista (UNESP)
dc.description.affiliationDepartament of Biostatistic Institute of Biosciences Universidade Estadual Paulista (UNESP)
dc.description.affiliationDepartament of Animal Science University of Western São Paulo (UNOESTE)
dc.description.affiliationUnespDepartament of Pharmacology Institute of Biosciences Universidade Estadual Paulista (UNESP)
dc.description.affiliationUnespDepartament of Morphology Institute of Biosciences Universidade Estadual Paulista (UNESP)
dc.description.affiliationUnespDepartament of Biostatistic Institute of Biosciences Universidade Estadual Paulista (UNESP)
dc.identifier.doi10.1371/journal.pone.0202017
dc.rights.accessRightsAcesso aberto
dc.description.sponsorshipIdFAPESP: 2011/50964-0
dc.description.sponsorshipIdFAPESP: 50514-8
dc.identifier.scopus2-s2.0-85052796134
dc.identifier.file2-s2.0-85052796134.pdf
dc.relation.ispartofsjr1,164
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