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Slimmer or Fertile? Pharmacological Mechanisms Involved in Reduced Sperm Quality and Fertility in Rats Exposed to the Anorexigen Sibutramine

Borges, Cibele S. [UNESP]; Missassi, Gabriela [UNESP]; Pacini, Enio S. A. [UNESP]; Kiguti, Luiz Ricardo A. [UNESP]; Sanabria, Marciana [UNESP]; Silva, Raquel F. [UNESP]; Banzato, Thais P. [UNESP]; Perobelli, Juliana E. [UNESP]; Pupo, André S. [UNESP]; Kempinas, Wilma G. [UNESP] (PLOS ONE, 2013-06-12) [Artigo]

Sperm acquire motility and fertility capacity during epididymal transit, under the control of androgens and sympathetic innervations. It is already known that the acceleration of epididymal sperm transit time can lead to ...