Now showing items 1-6 of 6
Differential morphofunctional characteristics and gene expression in fast and slow muscle of rats with monocrotaline-induced heart failure
(Journal of Molecular Histology, 2011-06-01) [Artigo]
Heart failure (HF) is characterized by limited exercise tolerance, skeletal muscle atrophy, a shift toward fast muscle fiber, and myogenic regulatory factor (MRF) changes. Reactive oxygen species (ROS) also contribute to ...
Combined effects of age and diet-induced obesity on biochemical parameters and cardiac energy metabolism in rats
(Indian Journal of Biochemistry and Biophysics, 2013-02-01) [Artigo]
Obesity is often associated with decreased fat oxidation and aging is a well-recognized risk factor for cardiovascular disease. This study investigated calorimetric and morphometric parameters, as well as the glucose levels, ...
Energy restriction and impact on indirect calorimetry and oxidative stress in cardiac tissue in rat
(Indian Journal Of Biochemistry & Biophysics, 2014-10-01) [Artigo]
Caloric restriction, defined as a reduction in calorie intake below ad libitum, without malnutrition can have beneficial effects. In this study, we evaluated the impact of caloric restriction of 30 and 60% on calorimetric ...
Beneficial effects of N-acetylcysteine on hepatic oxidative stress in streptozotocin-induced diabetic rats
(Canadian Journal of Physiology and Pharmacology, 2018-01-01) [Artigo]
Diabetes is one of the leading diseases worldwide and, thus, finding new therapeutic alternatives is essential. The development of non-alcoholic fatty liver disease is a notable diabetic complication. Therefore, antioxidant ...
Tobacco Smoke Induces Ventricular Remodeling Associated with an Increase in NADPH Oxidase Activity
(Cellular Physiology and Biochemistry, 2011-01-01) [Artigo]
Background: Recent studies have assessed the direct effects of smoking on cardiac remodeling and function. However, the mechanisms of these alterations remain unknown. The aim of this study was to investigate de role of ...
Diabetes mellitus activates fetal gene program and intensifies cardiac remodeling and oxidative stress in aged spontaneously hypertensive rats
(Cardiovascular Diabetology, 2013-10-17) [Artigo]
Background: The combination of systemic arterial hypertension and diabetes mellitus (DM) induces greater cardiac remodeling than either condition alone. However, this association has been poorly addressed in senescent rats. ...