Mastocitoma canino: estudo retrospectivo dos casos atendidos pelo serviço de oncologia do hospital veterinário da FCAV-Unesp-Câmpus de Jaboticabal no período de 2005 a 2015
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2016-02-23
Autores
Souza, Ana Carolina Furtado de
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Universidade Estadual Paulista (Unesp)
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Este estudo teve como objetivo analisar os casos de mastocitomas em 192 cães atendidos no Hospital Veterinário Governador Laudo Natel da Faculdade de Ciências Agrárias e Veterinárias (FCAV)-UNESP-Câmpus Jaboticabal, no período de 2005 a 2015, além de analisar a ocorrência dessa neoplasia em relação à raça, idade e sexo; determinar quais as regiões corpóreas foram mais acometidas e as características neoplásicas observadas; avaliar quais são os métodos de diagnóstico mais utilizados no setor; estabelecer os principais graus histológicos diagnosticados, os tratamentos preconizados, avaliar a taxa de recidiva e metástase. Foram avaliados 192 pacientes e foi observado que setenta e seis animais apresentavam múltiplos nódulos (39,6%), e os nódulos acima de três centímetros perfaziam 39,1% das amostras (n=75). Sessenta e um casos de lesões metastáticas em linfonodos regionais – N1 (31,8%) foram encontrados e 71,9% dos nódulos identificados tiveram crescimento rápido, sendo 16,7% (n= 32) localizados em membro pélvico. Foi observada associação estatística entre a presença de nódulos solitários/múltiplos e o grau histológico segundo Kiupel et al. (2011) (p=0,004). Em relação à classificação de Patnaik et al. (1984), as variáveis raça e sexo diferem proporcionalmente entre os grupos histológicos (p=0,008 e 0,040 respectivamente), a presença de linfonodo comprometido por metástase e velocidade de crescimento rápido também tiveram associação com o grau histológico (p=0,002 e 0,001). Além disto, foi observado também associação entre a classificação histológica e o tamanho (p=0,001), a consistência (p=0,028) e a velocidade de crescimento do nódulo (p<0,001), e entre a presença de nódulos múltiplos com estadio II ou IV (p<0,001) e presença de recidiva (p= 0,001). Estudos retrospectivos são de grande importância para que se possa compreender através de dados estatísticos o comportamento de neoplasias, minimizando ou prevenindo a ocorrência em nossos pacientes.
This kind of study has had as target the analyze of the mast cell tumors case in 192 (one hundred and ninety-two) dogs. They have been treated in the Veterinary Hospital Governador Laudo Natel – in the College of Agrarian Science and Veterinary (FCAV) - UNESP - Campus Jaboticabal, from 2005 to 2015. Besides having analysed the case frequency of neoplasia in relation to the breed, age and sex; having determined which body areas were most affected and neoplastic characteristics observed; having established the main histologic the degrees diagnosed, the most indicated treatments; having evaluated the rate of reappearance and metastasis. 192(one hundred and ninety-two) patients have been evaluated and it has been noticed that 76 (seventy-six) animals presented multiple nodules (39,6%). The nodules above 3 (three) centimeters made up 39,1% of the samples (n=75). Sixty-one cases of metastatic lesions in specific areas of lymph nodes - N1 (31,8%) have been found; and 71,9% of identified nodules showed fast growth, and 16,7% (n = 32) located in the pelvic limb. It was been observed the statistics association between the presence of nodules solitary / multiple and histologic degree according to Kiupel et al (2011) (p= 0,004). As far as Patnaik et al classification (1984) is concerned, several types of breed and sex differ proportionally among the histologic groups (p=0,008 and 0,040 respectively), the presence of lymph node fully involved by metastasis and a great speed of fast growing process has also association with the histologic degree (p=0,002 and 0,001). It was also viewed the association between the histologic classification and the size (p=0,001),the consistence (p=0,028) and the velocity of the nodule growth (p<0,001). Moreover, the association between the presence of multiple nodules in the level II or IVwith the mapping of the disease (p<0,001) and the return of the reappearance (p=0,001). Retrospective studies are extremely relevant in order to acquire the understand through statistic data about the how neoplasias occur, if they minimize or prevent the cases in our patients. Keywords: sarcoma; neoplasia; mast cell; dogs.
This kind of study has had as target the analyze of the mast cell tumors case in 192 (one hundred and ninety-two) dogs. They have been treated in the Veterinary Hospital Governador Laudo Natel – in the College of Agrarian Science and Veterinary (FCAV) - UNESP - Campus Jaboticabal, from 2005 to 2015. Besides having analysed the case frequency of neoplasia in relation to the breed, age and sex; having determined which body areas were most affected and neoplastic characteristics observed; having established the main histologic the degrees diagnosed, the most indicated treatments; having evaluated the rate of reappearance and metastasis. 192(one hundred and ninety-two) patients have been evaluated and it has been noticed that 76 (seventy-six) animals presented multiple nodules (39,6%). The nodules above 3 (three) centimeters made up 39,1% of the samples (n=75). Sixty-one cases of metastatic lesions in specific areas of lymph nodes - N1 (31,8%) have been found; and 71,9% of identified nodules showed fast growth, and 16,7% (n = 32) located in the pelvic limb. It was been observed the statistics association between the presence of nodules solitary / multiple and histologic degree according to Kiupel et al (2011) (p= 0,004). As far as Patnaik et al classification (1984) is concerned, several types of breed and sex differ proportionally among the histologic groups (p=0,008 and 0,040 respectively), the presence of lymph node fully involved by metastasis and a great speed of fast growing process has also association with the histologic degree (p=0,002 and 0,001). It was also viewed the association between the histologic classification and the size (p=0,001),the consistence (p=0,028) and the velocity of the nodule growth (p<0,001). Moreover, the association between the presence of multiple nodules in the level II or IVwith the mapping of the disease (p<0,001) and the return of the reappearance (p=0,001). Retrospective studies are extremely relevant in order to acquire the understand through statistic data about the how neoplasias occur, if they minimize or prevent the cases in our patients. Keywords: sarcoma; neoplasia; mast cell; dogs.
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Tumor de células redondas, Neoplasia, Mastócito, Cães