Avaliação ocular com elastografia acoustic radiation force impulse (ARFI) do glaucoma secundário crônico em cães
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Data
2020-07-17
Autores
Madruga, Gabriela Morais [UNESP]
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Universidade Estadual Paulista (Unesp)
Resumo
A síndrome glaucomatosa em cães cursa com o aumento de pressão intraocular (PIO), ensejando alterações nos tecidos intraoculares, além de repercussões como a perda visual e dor. O objetivo deste estudo foi avaliar e comparar a elasticidade do nervo óptico (NO) e do complexo retina-coroide-esclera (CRCE) em cães com olhos saudáveis e com glaucoma secundário utilizando a elastografia ARFI. O estudo foi composto por 50 olhos (25 saudáveis e 25 glaucomatosos), os valores médios de velocidade de cisalhamento (VC) foram comparados entre os grupos pelo teste t de Student e verificou-se a correlação entre as medidas de elastografia das estruturas e a PIO dos olhos glaucomatosos. A VC do NO em olhos glaucomatosos foi de 4,77 ± 1,59 m/s, sendo significativamente maior do que dos olhos saudáveis (2,34 ± 0,45 m/s - p<0,0001). As médias de VC do CRCE em cães com glaucoma e saudáveis foram de 4,26 ± 1,28 m/s e 2,36 ± 0,40 m/s), respectivamente, demonstrando aumento significativo da rigidez para os olhos glaucomatosos (p<0,0001). A VC do NO e do CRCE não se correlacionaram com as variáveis obtidas ao modo B (tamanho do bulbo ocular, câmara vítrea e NO) e com a PIO (p>0,05). Entretanto, nos olhos glaucomatosos observou-se discreta correlação positiva entre a velocidade de cisalhamento do NO e do CRCE (r=0,38, p=0,05). Os valores de VC dos tecidos do NO e do CRCE em olhos glaucomatosos são maiores do que em olhos sadios, sugerindo que são menos elásticos, ou mais duros.
Secondary glaucoma syndrome in dogs is accompanied by an increase in ocular pressure (IOP), which causes changes in the intraocular tissues, as well as repercussions such as vision loss and discomfort. The aim of this study was to evaluate and compare the elasticity of the optic nerve (ON) and retinalchoroid-sclera complex (RCSC) in dogs with healthy eyes and secondary glaucoma using ARFI elastography. The study consisted of 50 eyes (25 healthy and 25 glaucomatous), the mean values of shear wave velocity (SWV) were compared between the groups by the Student's t-test and the correlation between the elastography measurements of the structures and the IOP of the glaucomatous eyes. The SWV of the ON in glaucomatous eyes was 4.77 ± 1.59 m/s, being significantly higher than in healthy eyes (2.34 ± 0.45 m/s) (p <0.0001). RCSC shear wave velocity values in glaucoma and healthy dogs were 4.26 ± 1.28 m / s and 2.36 ± 0.40 m/s, respectively, demonstrating increased stiffness for glaucomatous group (p<0,0001). The SWV of ON and RCSC did not correlate with the variables obtained in mode B (size of eye bulb, glass chamber and ON) and with the IOP (p>0.05). However, in the glaucomatous eyes it was observed a discrete positive correlation between the ON and RCSC shear speed in the correlation (r=0.38, p=0.05). The SWV values of ON and RCSC tissues in glaucomatous eyes are greater than in healthy eyes, suggesting that they are less elastic or harder in glaucomatous eyes
Secondary glaucoma syndrome in dogs is accompanied by an increase in ocular pressure (IOP), which causes changes in the intraocular tissues, as well as repercussions such as vision loss and discomfort. The aim of this study was to evaluate and compare the elasticity of the optic nerve (ON) and retinalchoroid-sclera complex (RCSC) in dogs with healthy eyes and secondary glaucoma using ARFI elastography. The study consisted of 50 eyes (25 healthy and 25 glaucomatous), the mean values of shear wave velocity (SWV) were compared between the groups by the Student's t-test and the correlation between the elastography measurements of the structures and the IOP of the glaucomatous eyes. The SWV of the ON in glaucomatous eyes was 4.77 ± 1.59 m/s, being significantly higher than in healthy eyes (2.34 ± 0.45 m/s) (p <0.0001). RCSC shear wave velocity values in glaucoma and healthy dogs were 4.26 ± 1.28 m / s and 2.36 ± 0.40 m/s, respectively, demonstrating increased stiffness for glaucomatous group (p<0,0001). The SWV of ON and RCSC did not correlate with the variables obtained in mode B (size of eye bulb, glass chamber and ON) and with the IOP (p>0.05). However, in the glaucomatous eyes it was observed a discrete positive correlation between the ON and RCSC shear speed in the correlation (r=0.38, p=0.05). The SWV values of ON and RCSC tissues in glaucomatous eyes are greater than in healthy eyes, suggesting that they are less elastic or harder in glaucomatous eyes
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Palavras-chave
Buftalmia, Caninos, Cegueira, Inflamação, Pressão intraocular, Ultrassonografia ocular