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dc.contributor.authorDessordi, Renata [UNESP]
dc.contributor.authorSantana, Rodrigo de Carvalho
dc.contributor.authorNavarro, Anderson Marliere [UNESP]
dc.date.accessioned2020-12-10T17:03:39Z
dc.date.available2020-12-10T17:03:39Z
dc.date.issued2019-01-01
dc.identifierhttp://dx.doi.org/10.1590/0037-8682-0441-2018
dc.identifier.citationRevista Da Sociedade Brasileira De Medicina Tropical. Brasilia: Soc Brasileira Medicina Tropical, v. 52, 6 p., 2019.
dc.identifier.issn0037-8682
dc.identifier.urihttp://hdl.handle.net/11449/195070
dc.description.abstractHepatitis B is a major public health problem worldwide and associated with significant mortality. To prevent or delay the deleterious effects of chronic infection by the hepatitis B virus, patients should be carefully followed, and antiviral therapy indicated according to specific recommendations. Currently, available drugs inhibit viral replication and slow or stop the progression of inflammation and fibrosis of the liver. However, the drugs for oral use in the treatment of hepatitis B. jointly referred to as nucleoside/nucleotide analogs, are indicated for prolonged use and have potential side effects. The reduction in bone mineral density was associated with the use of tenofovir, already evaluated in patients infected with HIV because the drug is also part of the therapeutic arsenal for this viral infection. There are few studies on the effects of tenofovir in patients with mono hepatitis B. Therefore, this literature review proposes to examine how hepatitis B acts in the body and the mechanisms by which antiretroviral drugs (especially tenofovir) can affect bone metabolism.en
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent6
dc.language.isoeng
dc.publisherSoc Brasileira Medicina Tropical
dc.relation.ispartofRevista Da Sociedade Brasileira De Medicina Tropical
dc.sourceWeb of Science
dc.subjectTenofovir
dc.subjectHepatitis B
dc.subjectBone metabolism
dc.subjectBone health
dc.titleInfluence of antiretroviral therapy on bone metabolism of patients with chronic hepatitis B: a reviewen
dc.typeResenha
dcterms.rightsHolderSoc Brasileira Medicina Tropical
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.description.affiliationUniv Estadual Paulista, Programa Posgrad Stricto Sensu Alimentos & Nutr, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Ciencias Farmaceut Estado Sao Paulo, Dept Alimentos & Nutr, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Sao Paulo, Dept Clin Med, Escola Med Ribeirao Preto, Ribeirao Preto, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Programa Posgrad Stricto Sensu Alimentos & Nutr, Sao Paulo, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Ciencias Farmaceut Estado Sao Paulo, Dept Alimentos & Nutr, Sao Paulo, SP, Brazil
dc.identifier.doi10.1590/0037-8682-0441-2018
dc.identifier.scieloS0037-86822019000100203
dc.identifier.wosWOS:000504014700001
dc.rights.accessRightsAcesso aberto
dc.description.sponsorshipIdCAPES: 001
dc.description.sponsorshipIdFAPESP: 2016/19284-7
dc.identifier.fileS0037-86822019000100203.pdf
unesp.author.orcid0000-0003-1157-1418[1]
unesp.author.orcid0000-0001-9127-3001[3]
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