Exibindo os resultados de 1 a 6 de 6
Abamectin affects the bioenergetics of liver mitochondria: A potential mechanism of hepatotoxicity
(Toxicology in Vitro, 2012-02-01) [Artigo]
Abamectin (ABA) is a macrocyclic lactone of the avermectin family used worldwide as an antiparasitic agent in farm animals and pets and as the active ingredient of insecticides and nematicides. In this study, the effects ...
Mechanism for the uncoupling of oxidative phosphorylation by juliprosopine on rat brain mitochondria
(Toxicon, 2012-12-15) [Artigo]
Prosopis juliflora, popularly known as Algaroba, is a major problem because the lack of food during the driest times of the year and its high palatability and nutritional value make its fruits (pods) much appreciated by ...
Cytotoxicity of monocrotaline in isolated rat hepatocytes: Effects of dithiothreitol and fructose
(Toxicon, 2011-06-01) [Artigo]
Monocrotaline (MCT) is a pyrrolizidine alkaloid present in plants of the Crotalaria species that causes cytotoxicity and genotoxicity, including hepatotoxicity in animals and humans. It is metabolized by cytochrome P-450 ...
Comparative effects of lantadene A and its reduced metabolite on mitochondrial bioenergetics
(Toxicon, 2010-06-15) [Artigo]
Lantana (Lantana camara Linn.) is a noxious weed to which certain medicinal properties have been attributed, but its ingestion has been reported to be highly toxic to animals and humans, especially in the liver. The main ...
Comparative effects of fipronil and its metabolites sulfone and desulfinyl on the isolated rat liver mitochondria
(Environmental Toxicology And Pharmacology, 2015) [Artigo]
Fipronil is an insecticide extensively used to control pests in crops and animals. There are relates of poisoning due to exposure of fipronil in mammals and the liver has been suggested as potential target. In this study, ...
Iron chelating-mediated antioxidant activity of Plectranthus barbatus extract on mitochondria
(Food Chemistry, 2010-09-01) [Artigo]
Plectranthus barbatus Andrews (Lamiaceae) is a popular medicinal plant used to treat gastrointestinal and hepatic ailments. In this work, we assessed the antioxidant activity of the aqueous extract of P. barbatus leaves ...