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Alterações hematológicas e sua relação com anormalidades oculares em pacientes infectados naturalmente com ehrlichia canis

dc.contributor.authorPiso, Dunia Yisela Trujillo
dc.contributor.authorBarreto, Monica Yamile Padilla
dc.contributor.authorBonilla, Maria Del Pilar Sánchez
dc.contributor.authorde Andrade, Alexandre Lima [UNESP]
dc.date.accessioned2021-06-25T10:31:58Z
dc.date.available2021-06-25T10:31:58Z
dc.date.issued2021-01-01
dc.identifierhttp://dx.doi.org/10.1590/0103-8478cr20200651
dc.identifier.citationCiencia Rural, v. 51, n. 8, 2021.
dc.identifier.issn1678-4596
dc.identifier.issn0103-8478
dc.identifier.urihttp://hdl.handle.net/11449/206434
dc.description.abstractTo determine the association between ocular abnormalities and hematologic findings in Ehrlichia canis-infected dogs, 120 dogs suspected of canine ehrlichiosis were studied. All patients were subjected to rapid serologic diagnostic test for Ehrlichia canis, and the diagnosis was confirmed by quantitative PCR. PCR-positive patients underwent ophthalmologic examination and a hemogram and were grouped into patients with thrombocytopenia and anemia (G1), patients with thrombocytopenia (G2), and patients without hematologic disorders (G3). For ophthalmic evaluation, the patients were grouped into those having mild, severe, both mild and severe, and no ocular alterations. All patients presented with uveitis (100%). Severe ocular disorders predominated in G1 and G2 patients. Dogs with anemia and leukopenia showed severe ocular disorders. In dogs with a greater number of leukocytes and copies/µl of the TRAG gene, the intraocular pressure (IOP) tends to decrease and vice versa (r = −0.23, r = −0.26). In conclusion, uveitis is the earliest ocular alteration of canine ehrlichiosis. The severity of ocular abnormalities in patients with ehrlichiosis is associated with thrombocytopenia and may be aggravated by anemia and leukopenia. The hemogram and IOP are useful tools for predicting eye involvement in Ehrlichia canis-infected patients. In regions where Ehrlichia canis is endemic, the use of the tonometer should be routinely in dog general consultation.en
dc.language.isoeng
dc.relation.ispartofCiencia Rural
dc.sourceScopus
dc.subjectEhrlichia
dc.subjectHematology
dc.subjectIOP
dc.subjectThrombocytopenia
dc.subjectTRAG gene
dc.subjectUveitis
dc.titleRelationship between ocular abnormalities and hematologic alterations in patients infected naturally by ehrlichia canisen
dc.titleAlterações hematológicas e sua relação com anormalidades oculares em pacientes infectados naturalmente com ehrlichia canispt
dc.typeArtigo
dc.contributor.institutionCooperative University of Colombia (UCC)
dc.contributor.institutionUniversidade Federal Rural do Rio de Janeiro (UFRRJ)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationCollege of Veterinary Medicine and Animal Science Impronta Research Group Cooperative University of Colombia (UCC)
dc.description.affiliationFaculdade de Medicina Veterinária Universidade Federal Rural do Rio de Janeiro (UFRRJ)
dc.description.affiliationDepartamento de Clínica Animal Cirurgia e Reprodução Faculdade de Medicina Veterinária Universidade Estadual Paulista (UNESP)
dc.description.affiliationUnespDepartamento de Clínica Animal Cirurgia e Reprodução Faculdade de Medicina Veterinária Universidade Estadual Paulista (UNESP)
dc.identifier.doi10.1590/0103-8478cr20200651
dc.identifier.scieloS0103-84782021000800601
dc.rights.accessRightsAcesso aberto
dc.identifier.scopus2-s2.0-85107211879
dc.identifier.fileS0103-84782021000800601.pdf
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