Now showing items 1-10 of 48
A systematic study of transfection efficiency and cytotoxicity in HeLa cells using iron oxide nanoparticles prepared with organic and inorganic bases
(Colloids and Surfaces B: Biointerfaces, 2012-12-01) [Artigo]
Magnetic iron oxide nanoparticles (magnetite) (MNPs) were prepared using different organic and inorganic bases. Strong inorganic base (KOH) and organic bases (NH4OH and 1,4-diazabicyclo[2.2.2]octane (DABCO)) were used in ...
Expression of TERT in precancerous gastric lesions compared to gastric cancer
(Brazilian Journal of Medical and Biological Research, 2011-02-01) [Artigo]
The objective of this study was to determine the levels of TERT mRNA and TERT protein expression in stomach precancerous lesions such as intestinal metaplasia (IM) and gastric ulcer (GU) and compare them to gastric cancer ...
Seasonality of viral respiratory infections in Southeast of Brazil: the influence of temperature and air humidity
(Brazilian Journal of Microbiology, 2012-03-01) [Artigo]
Viruses are the major cause of lower respiratory tract infections in childhood and the main viruses involved are Human Respiratory Syncytial Virus (HRSV), Human Metapneumovirus (HMPV), Influenzavirus A and B (FLUA and ...
Hepatitis C Virus NS2 Protein Inhibits DNA Damage Pathway by Sequestering p53 to the Cytoplasm
(PLOS ONE, 2013-04-30) [Artigo]
Chronic hepatitis C virus (HCV) infection is an important cause of morbidity and mortality globally, and often leads to end-stage liver disease. The DNA damage checkpoint pathway induces cell cycle arrest for repairing DNA ...
Expression of annexin-A1 and galectin-1 anti-inflammatory proteins and mRNA in chronic gastritis and gastric cancer
(Mediators of Inflammation, 2013-03-07) [Artigo]
Objective. The anti-inflammatory proteins annexin-A1 and galectin-1 have been associated with tumor progression. This scenario prompted us to investigate the relationship between the gene and protein expression of annexin-A1 ...
Analysis of HCV quasispecies dynamic under selective pressure of combined therapy
(BMC Infectious Diseases, 2013-02-01) [Artigo]
Background: The quasispecies composition of Hepatitis C virus (HCV) could have important implications with regard to viral persistence and response to interferon-based therapy. The complete NS5A was analyzed to evaluate ...
Papel da proteína Mx1 na resposta a interferons e no processo neoplásico
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2011-12-01) [Artigo]
The Mx1 protein is encoded by an interferon- induced gene and shares domain organization, homooligomerization capacity and membrane association with the large dynamin-like GTPases. The Mx1 protein is involved in the response ...
Expressão dos genes que codificam as proteínas anexina-1 e galectina-1 nos pólipos rinossinusais e sua modulação pelo glicocorticoide
(Brazilian Journal of Otorhinolaryngology, 2010-04-01) [Artigo]
A fisiopatologia da polipose rinossinusal não é totalmente compreendida, apesar de várias hipóteses em relação ao seu processo inflamatório. OBJETIVOS: Estudo prospectivo da expressão dos genes das proteínas, anexina-1 e ...
Sistema de informação geográfica aplicado a banco de tumores
(Congresso de Extensão Universitária, 2011) [Trabalho apresentado em evento]
Structural studies of Helicase NS3 variants from Hepatitis C virus genotype 3 in virological sustained responder and non-responder patients
(BMC Research Notes, 2010-08-19) [Artigo]
Background. About 130 million people are infected with the hepatitis C virus (HCV) worldwide, but effective treatment options are not yet available. One of the most promising targets for antiviral therapy is nonstructural ...