Now showing items 1-10 of 20
Long-term effects of developmental exposure to di-n-butyl-phthalate (DBP) on rat prostate: Proliferative and inflammatory disorders and a possible role of androgens
(Toxicology, 2009-08-21) [Artigo]
In the present study we evaluated the toxic effects on the male adult rat prostate of DBP exposure during fetal and lactational periods, because although many studies have addressed the influence of phthalates on the male ...
MMP-2 and TIMP-2 in male and female prostates of mongolian gerbil: effects of hormonal manipulation
(Histology and Histopathology, 2011) [Artigo]
TIMPs in the prostates of male and female gerbils and evaluated the effects of testosterone on the expression of these enzymes. Ventral prostates from male gerbils that were either intact or had been castrated for 7 or 21 ...
Mast Cells and Ethanol Consumption: Interactions in the Prostate, Epididymis and Testis of UChB Rats
(American Journal of Reproductive Immunology, 2011-09-01) [Artigo]
ProblemAlcoholism has reached alarming proportions while fertility rates slowing in populations. The assessment of inflammatory effects with emphasis on the variation of the mast cells comparing ethanol chronic ingestion ...
Functional and Morphological Reproductive Aspects in Male Rats Exposed to Di-n-Butyl Phthalate (DBP) in Utero and During Lactation
(Journal of Toxicology and Environmental Health: Part A Current Issues, 2010-01-01) [Artigo]
The potential adverse reproductive effects, with emphasis on the epididymis, of in utero and lactational exposure to 100 mg/kg/d di-n-butyl phthalate (DBP) in adult male rat offspring were investigated. The fetal testis ...
MOMO syndrome associated with autism: a case report
(Genetics and Molecular Research, 2008-01-01) [Artigo]
This is a case report of macrosomia, obesity, macrocephaly and ocular abnormalities (MOMO syndrome) associated with autism. Studies on genetic or environmental syndromes associated with autism can provide genetic markers ...
Structural and ultrastructural evidence for telocytes in prostate stroma
(Journal of Cellular and Molecular Medicine, 2013-03-01) [Artigo]
The prostate comprises a glandular epithelium embedded within a fibromuscular stroma. The stroma is a complex arrangement of cells and extracellular matrix (ECM) components in addition to growth factors, regulatory molecules, ...
Ionotropic but not metabotropic glutamatergic receptors in the locus coeruleus modulate the hypercapnic ventilatory response in unanaesthetized rats
(Acta Physiologica, 2013-05-01) [Artigo]
Aim: Central chemoreceptors are important to detect changes of CO2/H+, and the Locus coeruleus (LC) is one of the many putative central chemoreceptor sites. Here, we studied the contribution of LC glutamatergic receptors ...
Gestational and lactational exposition to Di-N-butyl-phthalate (DBP) increases inflammation and preneoplastic lesions in prostate of wistar rats after carcinogenic N-methyl-N-nitrosourea (MNU) plus testosterone protocol
(Environmental Toxicology, 2015-03-02) [Artigo]
In the present study, it was evaluated the susceptibility of prostatic lesions in male adult rats exposed to Di-N-butyl-phthalate during fetal and lactational periods and submitted to MNU plus testosterone carcinogenesis ...
Prostatic stromal cells of old gerbils respond to steroidal blockades creating a microenvironment similar to reactive stroma
(Biomedicine and Aging Pathology, 2011-04-01) [Artigo]
The present study examined the changes in prostatic stroma of old gerbils (18 months) submitted to orchiectomy associated or not with steroidal blockades. Animals were divided into six groups, all surgically castrated ...
Ionotropic but not metabotropic glutamatergic receptors in the Locus Coeruleus modulate the hypercapnic ventilatory response in unanesthetized rats
(FASEB Journal, 2013-04-01) [Resumo]