Now showing items 1-6 of 6
Prostatic stromal cells of old gerbils respond to steroidal blockades creating a microenvironment similar to reactive stroma
(Biomedicine and Aging Pathology, 2011-04-01) [Artigo]
The present study examined the changes in prostatic stroma of old gerbils (18 months) submitted to orchiectomy associated or not with steroidal blockades. Animals were divided into six groups, all surgically castrated ...
Structural and ultrastructural evidence for telocytes in prostate stroma
(Journal of Cellular and Molecular Medicine, 2013-03-01) [Artigo]
The prostate comprises a glandular epithelium embedded within a fibromuscular stroma. The stroma is a complex arrangement of cells and extracellular matrix (ECM) components in addition to growth factors, regulatory molecules, ...
Gestational and lactational exposition to Di-N-butyl-phthalate (DBP) increases inflammation and preneoplastic lesions in prostate of wistar rats after carcinogenic N-methyl-N-nitrosourea (MNU) plus testosterone protocol
(Environmental Toxicology, 2015-03-02) [Artigo]
In the present study, it was evaluated the susceptibility of prostatic lesions in male adult rats exposed to Di-N-butyl-phthalate during fetal and lactational periods and submitted to MNU plus testosterone carcinogenesis ...
MMP-2 and TIMP-2 in the prostates of male and female mongolian gerbils: Effects of hormonal manipulation
(Histology and Histopathology, 2011-11-01) [Artigo]
TIMPs in the prostates of male and female gerbils and evaluated the effects of testosterone on the expression of these enzymes. Ventral prostates from male gerbils that were either intact or had been castrated for 7 or 21 ...
MMP-2 and MMP-9 localization and activity in the female prostate during estrous cycle
(General and Comparative Endocrinology, 2011-09-15) [Artigo]
The gerbil female prostate undergoes morphological and physiological changes resulting from hormonal fluctuations that occur during the reproductive cycle. These repetitive cycles of glandular growth and regression are ...
A new proposed rodent model of chemically induced prostate carcinogenesis: Distinct time-course prostate cancer progression in the dorsolateral and ventral lobes
(Prostate, 2013-08-01) [Artigo]
Background. Characterization of novel rodent models for prostate cancer studies requires evaluation of either spontaneous and carcinogen-induced tumors as well as tumor incidence in different prostatic lobes. We propose a ...