Now showing items 1-10 of 339
Analysis of CDKN1A polymorphisms: markers of cancer susceptibility?
(Cancer Genetics and Cytogenetics, 2003-04-15) [Artigo]
The CDKN1A (TP21)(2) gene encodes a 21-kD protein that is a critical downstream mediator of wild-type TP53 and an important regulator of the cell cycle. Failure in the function of this gene would be expected to result in ...
Evaluation of fitness components in strains of Drosophila mulleri carrying different genotypes for an esterase
(Cytobios, 2001-01-01) [Artigo]
Several fitness components in strains of Drosophila mulleri carrying the slow or the fast alleles for the major beta esterase (esterase-4) found in this species, as well as in heterozygous flies in which the slow or fast ...
Experimental endocrine therapies promote epithelial cytodifferentiation and ciliogenesis in the gerbil female prostate
(Cell and Tissue Research, 2007-06-01) [Artigo]
The incidence of ciliated cells in the prostate gland of the female gerbil (Meriones unguiculatus) is uncommon and apparently becomes more frequent during androgen (testosterone cypionate) and anti-estrogen (letrozole) ...
Aneuploidies, deletion, and overexpression of TP53 gene in intestinal metaplasia of patients without gastric cancer
(Cancer Genetics and Cytogenetics, 2004-09-01) [Artigo]
Gastric carcinogenesis is attributable to interacting environmental and genetic factors, through a sequence of events including intestinal metaplasia. Using a fluorescence in situ hybridization technique, we investigated ...
HFE gene mutations in Brazilian thalassemic patients
(Brazilian Journal of Medical and Biological Research, 2006-12-01) [Artigo]
Hereditary hemochromatosis is a disorder of iron metabolism characterized by increased iron intake and progressive storage and is related to mutations in the HFE gene. Interactions between thalassemia and hemochromatosis ...
Long-term effects of developmental exposure to di-n-butyl-phthalate (DBP) on rat prostate: Proliferative and inflammatory disorders and a possible role of androgens
(Toxicology, 2009-08-21) [Artigo]
In the present study we evaluated the toxic effects on the male adult rat prostate of DBP exposure during fetal and lactational periods, because although many studies have addressed the influence of phthalates on the male ...
Simultaneous observation of collagen and elastin in normal and pathological tissues: analysis of Sirius-red-stained sections by fluorescence microscopy
(Cell and Tissue Research, 2005-06-01) [Artigo]
In order to observe collagen and elastic fibers simultaneously, sections of human aorta, skin, lung, liver, and bladder were stained by Sirius red and analyzed by fluorescence microscopy. In all cases, the fibers of collagen ...
Cytogenetic alterations in chagasic achalasia compared to esophageal carcinoma
(Cancer Genetics and Cytogenetics, 2004-02-01) [Artigo]
Patients with chagasic achalasia (megaesophagus) are liable to have an additional 1.7-20% possibility of developing esophageal squamous cell carcinoma (ESCC). We applied a fluorescence in situ hybridization technique in ...
Analysis of human papillomavirus prevalence and TP53 polymorphism in head and neck squamous cell carcinomas
(Cancer Genetics and Cytogenetics, 2004-04-01) [Artigo]
Head and neck squamous cell carcinoma is a disease associated with tobacco and alcohol abuse. There is evidence that the oncogenic human papillomavirus (HPV) may also be a risk for upper aerodigestive tract cancers. High-risk ...
Registro documentado da marreca-de-asa-azul, Anas discors (Aves, Anatidae) no município de São Paulo
(Atualidades Ornitologicas, 2008-07-01) [Artigo]