The development of resistance to caffeine in Drosophila prosaltans: productivity and longevity after ten generations of treatment
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Data
1998-01-01
Autores
Itoyama, M. M.
Bicudo, HEMD
Manzato, A. J.
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Editor
Faculty Press
Resumo
The productivity of Drosophila prosaltans treated with six concentrations of caffeine (from 50 mu g/ml to 2,500 mu g/ml of culture medium) during ten generations (similar to 8 months) decreased in a dosage dependent manner in every generation, but at the end of the treatment the flies in all experiments recovered normal productivity, except for those treated with 2,500 mu g/ml. Longevity in the tenth generation was significantly reduced in males and females only in the 2,500 mu g/ml dosage, with males being much more affected than females. In a previous study in which the treatment was done in a single generation, productivity exhibited only a partial recovery when the treatment ceased and longevity was significantly reduced in 1,500 mu g/ml dosages. The hypothesis of selection occurring in ten generations leading to recovery in productivity and to a reduction in the processes which cause a decrease in longevity is being considered.
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Palavras-chave
Drosophila, productivity, longevity, caffeine
Como citar
Cytobios. Cambridge: Faculty Press, v. 96, n. 382, p. 81-93, 1998.