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dc.contributor.authorRodrigues Filho, E. A. [UNESP]
dc.contributor.authorStafuzza, N. B. [UNESP]
dc.contributor.authorCaetano, A. R.
dc.contributor.authorGill, C. A.
dc.contributor.authorRiggs, P. K.
dc.contributor.authorWomack, J. E.
dc.contributor.authorAmaral, M. E. J. [UNESP]
dc.date.accessioned2014-05-20T14:01:05Z
dc.date.available2014-05-20T14:01:05Z
dc.date.issued2008-01-01
dc.identifierhttp://www.karger.com/Article/Pdf/317181
dc.identifier.citationAnimal Genomics For Animal Health. Basel: Karger, v. 132, p. 343-346, 2008.
dc.identifier.issn1424-6074
dc.identifier.urihttp://hdl.handle.net/11449/21587
dc.description.abstractThe major histocompatibility complex (MHC) contains a set of genes necessary for antigen presentation in the immune system. This gene dense and polymorphic region of the mammalian genome is of considerable interest due to the role of MHC genes in immune function and animal health. Previous cytogenetic studies have indicated that the MHC in river buffalo resides on the short arm of chromosome 2 (BBU2). A 5000-rad radiation hybrid mapping panel was recently generated to enable construction of a whole genome map of river buffalo. To this and, the aims of this project were to elucidate the general organization of the MHC on BBU2, and to compare gene order within this region to the MHC in cattle. PCR primers were selected from the bovine gene map and used with the BBURH(5000) panel to map a set of ten MHC class 11 genes in river buffalo. Analysis indicates that these genes fall into two linkage groups, consistent with organization of the MHC in cattle. This comparison of buffalo and bovine MHC gene order provides the first insight into the organization of the MHC on river buffalo chromosome 2.en
dc.format.extent343-346
dc.language.isoeng
dc.publisherKarger
dc.relation.ispartofAnimal Genomics For Animal Health
dc.sourceWeb of Science
dc.subjectMHC genesen
dc.subjectRH mappingen
dc.subjectBBU2pen
dc.subjectRiver buffaloen
dc.titleMapping MHC Genes in River Buffaloen
dc.typeTrabalho apresentado em evento
dcterms.rightsHolderKarger
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationSão Paulo State Univ, UNESP, IBILCE, Depto Biol, Sao Jose do Rio Preto, Brazil
dc.description.affiliationUnespSão Paulo State Univ, UNESP, IBILCE, Depto Biol, Sao Jose do Rio Preto, Brazil
dc.identifier.wosWOS:000264184200044
dc.rights.accessRightsAcesso aberto
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Biociências Letras e Ciências Exatas, São José do Rio Pretopt
dc.identifier.lattes0175083848055466
unesp.author.lattes0175083848055466
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