The genetic diversity of Plasmodium vivax: a review
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Data
2007-06-01
Autores
Souza-Neiras, Wanessa Christina de [UNESP]
Melo, Luciane Moreno Storti de [UNESP]
Machado, Ricardo Luiz Dantas
Título da Revista
ISSN da Revista
Título de Volume
Editor
Instituto Oswaldo Cruz, Ministério da Saúde
Resumo
The genetic diversity of Plasmodium vivax has been investigated in several malaria-endemic areas, including the Brazilian Amazon region, where this is currently the most prevalent species causing malaria in humans. This review summarizes current views on the use of molecular markers to examine P. vivax populations, with a focus on studies performed in Brazilian research laboratories. We emphasize the importance of phylogenetic studies on this parasite and discuss the perspectives created by our increasing understanding of genetic diversity and population structure of this parasite for the development of new control strategies, including vaccines, and more effective drugs for the treatment of P. vivax malaria.
Descrição
Palavras-chave
Malaria, Plasmodium vivax, Genetic diversity, Molecular markers, Phylogeny, Evolution
Como citar
Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 102, n. 3, p. 245-254, 2007.